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David A. Nicewicz
Researcher at University of North Carolina at Chapel Hill
Publications - 102
Citations - 12980
David A. Nicewicz is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Catalysis & Photoredox catalysis. The author has an hindex of 39, co-authored 96 publications receiving 9680 citations. Previous affiliations of David A. Nicewicz include Peking University & Princeton University.
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Self-consistent synthesis of the squalene synthase inhibitor zaragozic acid C via controlled oligomerization.
TL;DR: In this article, the use of silyl glyoxylates as dipolar glycolic acid synthons in a controlled oligomerization reaction for the efficient construction of the squalene synthase inhibitor zaragozic acid C was described.
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Silyl Glyoxylates. Conception and Realization of Flexible Conjunctive Reagents for Multicomponent Coupling
Gregory R. Boyce,Stephen N. Greszler,Jeffrey S. Johnson,Xin Linghu,Justin T. Malinowski,David A. Nicewicz,Andrew Duncan Satterfield,Daniel C. Schmitt,Kimberly M. Steward +8 more
TL;DR: This Perspective describes the discovery and development of silyl glyoxylates, a new family of conjunctive reagents for use in multicomponent coupling reactions, and preliminary findings on the development of catalytic reactions using these reagents are detailed.
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Synthesis and Characterization of Acridinium Dyes for Photoredox Catalysis.
TL;DR: This work presents an efficient and scalable preparation of the most synthetically useful acridinium reported to date, utilizing the direct conversion of a xanthylium salt into the corresponding acrid inium as the key transformation.
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Reversing the Regioselectivity of Halofunctionalization Reactions through Cooperative Photoredox and Copper Catalysis
TL;DR: A reversal of the native regioselectivity for alkene halofunctionalization through the use of an acridinium photooxidant in conjunction with a copper cocatalyst is demonstrated.
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Organic Photoredox Catalysis as a General Strategy for Anti-Markovnikov Alkene Hydrofunctionalization.
TL;DR: A unique catalyst system comprised of an acridinium photooxidant and a hydrogen atom transfer reagent allows for a range of alkene anti-Markovnikov hydrofunctionalization reactions including hydroalkoxylation, hydroamination, and hydroacetoxylations.