D
David A. Sack
Researcher at National Institutes of Health
Publications - 48
Citations - 7453
David A. Sack is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Melatonin & Morning. The author has an hindex of 34, co-authored 48 publications receiving 7254 citations. Previous affiliations of David A. Sack include Heidelberg University.
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Journal ArticleDOI
Seasonal Affective Disorder: A Description of the Syndrome and Preliminary Findings With Light Therapy
Norman E. Rosenthal,David A. Sack,J. Christian Gillin,Alfred J. Lewy,Frederick K. Goodwin,Yolande B. Davenport,Peter S. Mueller,David A. Newsome,Thomas A. Wehr +8 more
TL;DR: Preliminary studies in 11 patients suggest that extending the photoperiod with bright artificial light has an antidepressant effect and sleep recordings in nine depressed patients confirmed the presence of hypersomnia and showed increased sleep latency and reduced slow-wave (delta) sleep.
Journal ArticleDOI
Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT).
Herbert Y. Meltzer,Larry Alphs,Alan I. Green,A. Carlo Altamura,Ravi Anand,Alberto Bertoldi,Marc Bourgeois,Guy Chouinard,M. Zahur Islam,John M. Kane,Ranga Krishnan,Jean-Pierre Lindenmayer,Steven G. Potkin,Saide Altinsan,Siemion Altman,Likiana Avigo,Richard Balon,Vanda Benešová,Luis Bengochea,István Bitter,Elisabeth Bokowska,Bernardo Carpiniello,Daniel E. Casey,Giovanni B. Cassano,James C.-Y. Chou,Libor Chvila,Jean Dalery,Pedro L. Delgado,Liliana Dell'Osso,Carl Eisdorfer,Robin Emsley,Dawn Eng,Tom A. Fahy,Vera Folnegovic,Sophie Frangou,Pedro Gargoloff,Alberto Giannelli,Ira D. Glick,Richard Greenberg,George T. Grossberg,Doris Gundersen,Hannale Heila,George Hsu,Naveed Iqbal,Miro Jakovljević,Richard C. Josiassen,Akos Kassaifarkas,Robert Kerwin,Frederic Khidichian,Mary Ann Knesevich,Jack S. Krasuski,Vinod Kumar,Veronica W. Larach,Michael D. Lesem,Shôn Lewis,Pierre-Michel Llorca,H. Edward Logue,Stephen Martin,Muriel Maurel-Raymondet,Laszlo Mod,Eva Morik,Carlos Morra,Ann M. Mortimer,Mojtaba Noursalehi,Gyorgy Ostorharics-Horvath,Ivo Paclt,Jörg Pahl,Linda Pestreich,J. L. Peters,Rosario Pioli,Michael G. Plopper,Thomas Posever,Mark Hyman Rapaport,Delbert Robinson,Carlo Andrea Robotti,Harry Rohme,Frédéric Rouillon,David A. Sack,Isaac Sakinsofsky,Phillip Seibel,George M. Simpson,Nancy Temkin,Oladapo Tomori,Santha Vaidain,Zdeòka Vyhnándová,Frederick Young,Daniel L. Zimbroff,Marie Agathe Zimmerman +87 more
TL;DR: It is suggested that clozapine therapy significantly reduces suicidal behavior in patients with schizophrenia and schizoaffective disorder at high risk for suicide, and use of clozAPine in this population should lead to a significant reduction in suicidal behavior.
Journal ArticleDOI
Sleep reduction as a final common pathway in the genesis of mania.
TL;DR: The sleep reduction model is a parsimonious explanation for the precipitation of manic episodes by a wide variety of factors and provides a conceptual focus and an experimental paradigm for psychological investigations of the causes of mania.
Journal Article
Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients
TL;DR: For 51 patients with rapid cycling affective disorder, clinical and family history data indicated that the illness was phenotypically and genetically related to more typical forms of affective disorders, was characterized by a bipolar course (100%), and was more common in women (92%).
Journal ArticleDOI
Antidepressant effects of light in seasonal affective disorder.
Norman E. Rosenthal,David A. Sack,Constance J. Carpenter,Barbara L. Parry,Wallace B. Mendelson,Thomas A. Wehr +5 more
TL;DR: The authors treated winter depression in patients with typical seasonal affective disorder by extending the length of winter days with bright and dim light in the morning and evening in a balanced-order crossover study, finding bright evening light alone is probably also effective.