Showing papers by "David Cohen published in 1991"

Law, Sexuality, and Society: The Enforcement of Morals in Classical Athens

Abstract: Centering on the examination of the social and legal context of adultery, homosexuality, impiety, and the public-private dichotomy in Athenian society, this book attempts to examine the problems of social control and the regulation of sexuality in a way that will be of interest to a broad readership. It uses a comparative approach to show how the examination of such issues can deepen our understanding of classical Athens, particularly in regard to the role of law in society. Further, it argues that this historical investigation can, in turn, enrich our general appreciation of the relation of social and legal norms, and the roles they play in regulating complex social practices, such as those associated with sexuality, morals and the family.

Soluble HLA antigens, anti-HLA antibodies, and antiidiotypic antibodies in the circulation of renal transplant recipients.

Abstract: Chronic rejection represents the major threat to long-term survival of organ allografts. It is presumed that this form of rejection is mediated by antibodies against mismatched HLA antigens of the graft. The presence and specificity of anti-HLA-antibodies in posttransplantation sera are, however, difficult to document. We have explored the possibility that anti-HLA antibodies form immune complexes with soluble HLA antigens released from the injured graft and/or that they are blocked by antiidiotypic, anti-anti-HLA-antibodies. Our data demonstrate that the long-term survival of renal allografts is significantly lower in patients who develop anti-HLA-antibodies following transplantation than in patients who do not form antibodies. Following depletion of soluble HLA antigens by magnetic immunoaffinity, we could identify anti-HLA-antibodies in 57% of the sera obtained from patients undergoing chronic rejection of kidney allografts, compared with 41% prior to antigen depletion. In patients tolerating the graft for 4 years or more, the corresponding frequencies of antibody-positive sera was 2% and 5% prior and following depletion of HLA antigens. The presence of HLA antigen/anti-HLA-antibody immune complexes in patients' sera was positively associated with chronic humoral rejection (P less than 0.0001). Patients who tolerated the graft in spite of having developed antibodies against one of its mismatched HLA antigens show specific antiidiotypic (anti-anti-HLA-antibodies). Such antiidiotypic antibodies were not found in sera from patients with chronic rejection (P = 0.005). This indicates that antiidiotypic antibodies may delay the progression of chronic humoral rejection.

Sexuality, Violence, and the Athenian Law of Hubris

Abstract: In recent years a considerable literature on the scope and meaning of the word hubris has done much to clarify the nature of this important concept. However, some important aspects of hubris deserve more detailed attention. In particular, a full account of the social context and moral psychology of the ideology, social practices, and legal prosecutions involving hubris would make a fundamental contribution to our understanding of Athenian society and the role which litigation played in moderating or exacerbating social conflicts. Indeed, such an account, particularly if it drew upon recent advances in the social anthropology of agonistic societies, would necessarily increase our appreciation of the centrality of hubris and the related values of honour and shame in Athenian social relations. While the goals of the present study are far more modest, in a sense they represent a first step in this direction. Since, as I will argue, the relation of the law of hubris to certain kinds of sexual misconduct and to sexual aspects of honour and shame has not been fully recognized, an exploration of this relation may help to mark out some of the ground which a fuller treatment would have to cover.