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David Cypcar
Researcher at University of Wisconsin-Madison
Publications - 7
Citations - 284
David Cypcar is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Immunology & Asthma. The author has an hindex of 4, co-authored 4 publications receiving 281 citations.
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Journal ArticleDOI
Steroid-resistant asthma
David Cypcar,William W. Busse +1 more
TL;DR: The development of medications with immunomodulatory effects on specific cellular functions represents an exciting step for more efficacious treatment for patients with corticosteroid-resistant asthma.
Journal ArticleDOI
Asthma and exercise.
David Cypcar,Robert F. Lemanske +1 more
TL;DR: Physical training should be part of the asthmatic patient's overall plan of management and should be able to participate or compete in the majority of sports, when properly treated.
Journal ArticleDOI
The impact of respiratory infections on asthma.
TL;DR: It is apparent that the effects of viral respiratory infections on the development of airway hyperresponsiveness are multiple and interrelated and involved the production of viral specific IgE, upregulation of leukocyte inflammatory activity, enhancement of the factors involved in the generation of late phase allergic responses, altered beta-adrenergic and cholinergic nervous system activity, and damage to the airway epithelium.
Journal ArticleDOI
Rat eosinophils: isolation and characterization of superoxide production
David Cypcar,Ronald L. Sorkness,Julie B. Sedgwick,Makoto Nagata,Jennifer Clough,Michael R. Kaplan,Robert F. Lemanske +6 more
TL;DR: Methods to obtain rat eosinophils with purity and viability exceeding 90%, characterized the superoxide anion production of these cells in response to standard activators, and compared these results with those previously obtained with the use of human eos inophils are developed.
Journal ArticleDOI
A Tyrosine Adsorbed Modified Grass Allergen + MPL SCIT Demonstrates Clinically Improvement in Combined Symptom and Medication Score in Subjects with Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis
Lawrence M. DuBuske,Stefan Zielen,Jonathan A. Bernstein,Uwe Berger,Markus Berger,Mandy Cuevas,David Cypcar,Annette Fuhr-Horst,William A Greisner,Margret Jandl,S. Lassmann,Margitta Worm,J. Matz,E. R. Sher,Christopher J. Tibbs nad Heather M. Smith.,Gary C. Steven,Kemi Oluwayi,Marion Seybold,Matthias F. Kramer,Murray A. Skinner,Pieter -Jan de Kam +20 more
TL;DR: An exploratory field study with a modified grass allergen subcutaneous immunotherapy (SCIT) product using MicroCrystalline Tyrosine (MCT) and Monophosphoryl Lipid A (MPL) as an adjuvant system was conducted to optimize a planned pivotal Phase III study as discussed by the authors .