R
Robert F. Lemanske
Researcher at University of Wisconsin-Madison
Publications - 339
Citations - 29528
Robert F. Lemanske is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Allergy. The author has an hindex of 86, co-authored 337 publications receiving 27178 citations. Previous affiliations of Robert F. Lemanske include Allegheny General Hospital & National Institutes of Health.
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Journal ArticleDOI
Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children
Daniel J. Jackson,Ronald E. Gangnon,Michael D. Evans,Kathy A. Roberg,Elizabeth L. Anderson,Tressa Pappas,Magnolia C. Printz,Wai Ming Lee,Peter Shult,Erik Reisdorf,Kirsten T. Carlson-Dakes,L.E.P. Salazar,Douglas F. DaSilva,Christopher J. Tisler,James E. Gern,Robert F. Lemanske +15 more
TL;DR: Among outpatient viral wheezing illnesses in infancy and early childhood, those caused by RV infections are the most significant predictors of the subsequent development of asthma at age 6 years in a high-risk birth cohort.
Journal ArticleDOI
Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome
Jan Lötvall,Cezmi A. Akdis,Leonard B. Bacharier,Leif Bjermer,Thomas B. Casale,Adnan Custovic,Robert F. Lemanske,Andrew J. Wardlaw,Sally E. Wenzel,Paul A. Greenberger +9 more
TL;DR: Criteria for defining asthma endotypes on the basis of their phenotypes and putative pathophysiology are suggested and how these new definitions can be used in clinical study design and drug development to target existing and novel therapies to patients most likely to benefit are proposed.
Journal ArticleDOI
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
Dara G. Torgerson,Dara G. Torgerson,Elizabeth J. Ampleford,Grace Y. Chiu,W. James Gauderman,Christopher R. Gignoux,Penelope E. Graves,Blanca E. Himes,Albert M. Levin,Rasika A. Mathias,Dana B. Hancock,Dana B. Hancock,Dana B. Hancock,James W. Baurley,Celeste Eng,Debra A. Stern,Juan C. Celedón,Nicholas Rafaels,Daniel Capurso,David V. Conti,Lindsey A. Roth,Manuel Soto-Quiros,Alkis Togias,Xingnan Li,Rachel A. Myers,Isabelle Romieu,Isabelle Romieu,David Van Den Berg,Donglei Hu,Nadia N. Hansel,Ryan D. Hernandez,Elliott Israel,Muhammad T. Salam,Joshua Galanter,Pedro C. Avila,Lydiana Avila,Jose R. Rodriquez-Santana,R. Chapela,William Rodríguez-Cintrón,Gregory B. Diette,N. Franklin Adkinson,Rebekah A. Abel,K. Ross,Min Shi,Mezbah U. Faruque,Georgia M. Dunston,Harold Watson,Vito J. Mantese,Serpil C. Ezurum,Liming Liang,Ingo Ruczinski,Jean G. Ford,Scott Huntsman,Kian Fan Chung,Hita Vora,Xia Li,William J. Calhoun,Mario Castro,Juan José Luis Sienra-Monge,Blanca Estela Del Río-Navarro,Klaus A. Deichmann,Andrea Heinzmann,Sally E. Wenzel,William W. Busse,William W. Busse,James E. Gern,Robert F. Lemanske,Terri H. Beaty,Eugene R. Bleecker,Benjamin A. Raby,Deborah A. Meyers,Stephanie J. London,Frank D. Gilliland,Esteban G. Burchard,Fernando D. Martinez,Scott T. Weiss,L. Keoki Williams,Kathleen C. Barnes,Carole Ober,Dan L. Nicolae +79 more
TL;DR: The results suggest that some asthma susceptibility loci are robust to differences in ancestry when sufficiently large samples sizes are investigated, and that ancestry-specific associations also contribute to the complex genetic architecture of asthma.
Journal ArticleDOI
A summary of the new GINA strategy: a roadmap to asthma control.
Helen K. Reddel,Eric D. Bateman,Allan B. Becker,Louis-Philippe Boulet,Alvaro A. Cruz,Jeffrey M. Drazen,Tari Haahtela,Suzanne S. Hurd,Hiromasa Inoue,Johan C. de Jongste,Robert F. Lemanske,Mark L Levy,Paul M. O'Byrne,Pierluigi Paggiaro,Søren Pedersen,Emilio Pizzichini,Manuel Soto-Quiroz,Stanley J. Szefler,Gary W.K. Wong,J. Mark FitzGerald +19 more
TL;DR: The changes include a revised asthma definition, tools for assessing symptom control and risk factors for adverse outcomes, and updated strategies for adaptation and implementation of GINA recommendations.
Journal ArticleDOI
Role of viral respiratory infections in asthma and asthma exacerbations
TL;DR: There is evidence that deficiencies in antiviral activity and the integrity of the airway epithelial barrier could make individuals with asthma more likely to have severe viral respiratory infections of the lower airway, and thus increase the risk of exacerbation.