David E. Clemmer

TL;DR: Ion mobility measurements can be used to obtain structural information for large polyatomic ions in the gas phase as mentioned in this paper, which can be applied to a wide range of chemical systems, such as atomic clusters and large biomolecules.

TL;DR: Ion mobility measurements have been used to obtain direct information about the conformers present for naked cytochrome c ions in the gas phase, and the results suggest that the gas-phase is an environment that will allow access to complementary information about protein conformations and the dynamics of protein folding as mentioned in this paper.

TL;DR: This review discusses how nonnative states differ in the gas phase compared with solution and presents an overview of early attempts to utilize and manipulate structures in order to develop ion mobility spectrometry as a rapid and sensitive technique for separating complex mixtures of biomolecules prior to mass Spectrometry.

TL;DR: In this article, the authors examined the geometries of naked BPTI (bovine pancreatic trypsin inhibitor) and cytochrome c ions in the gas phase, as a function of charge.

TL;DR: An ion mobility/mass spectrometry technique has been developed to record mass-resolved ion mobility distributions for multiple ions simultaneously, resulting in a three-dimensional spectrum that contains collision cross section, mass-to-charge, and ion abundance information.