D
David E. Parkin
Researcher at Aberdeen Royal Infirmary
Publications - 74
Citations - 4254
David E. Parkin is an academic researcher from Aberdeen Royal Infirmary. The author has contributed to research in topics: Endometrial ablation & Ovarian cancer. The author has an hindex of 26, co-authored 74 publications receiving 4089 citations.
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Recurrent Epithelial Ovarian Carcinoma: A Randomized Phase III Study of Pegylated Liposomal Doxorubicin Versus Topotecan
TL;DR: The comparable efficacy, favorable safety profile, and convenient dosing support the role of PLD as a valuable treatment option in patients with epithelial ovarian carcinoma that recurred after or didn't respond to first-line, platinum-based chemotherapy.
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Phase III Randomized Trial of Docetaxel–Carboplatin Versus Paclitaxel–Carboplatin as First-line Chemotherapy for Ovarian Carcinoma
Paul Vasey,Gordon C Jayson,Alan N. Gordon,Hani Gabra,Robert E. Coleman,Ronnie Atkinson,David E. Parkin,James Paul,A. Hay,Stan B. Kaye +9 more
TL;DR: In this article, the authors compared the combination of docetaxel-carboplatin and paclitaxel carboplatin as first-line chemotherapy for stage Ic-IV epithelial ovarian or primary peritoneal cancer.
Journal Article
On behalf of the Scottish Gynaecological Cancer Trials Group. Phase III Randomized Trial of Docetaxel?Carboplatin Versus Paclitaxel?Carboplatin as First-line Chemotherapy for Ovarian Carcinoma
Paul Vasey,Gordon C Jayson,Alan N. Gordon,Hani Gabra,Robert E. Coleman,Atkinson R,David E. Parkin,James Paul,A. Hay,S. B. Kaye +9 more
TL;DR: Docetaxe-carboplatin appears to be similar to paclitaxel- carboplatin in terms of progression-free survival and response, although longer follow-up is required for a definitive statement on survival.
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Diffusion-weighted magnetic resonance imaging in the early detection of response to chemoradiation in cervical cancer
TL;DR: DWI has potential to provide a surrogate biomarker of treatment response in advanced cervical cancers and offers an early and reproducible indication of tumour response which may ultimately allow the development of individualised regimens.
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Use of new imaging techniques to predict tumour response to therapy
TL;DR: Various new imaging techniques, such as diffusion-weighted MRI, dynamic contrast-enhanced MRI, magnetic resonance spectroscopy, and 18-fluorodeoxyglucose-PET as early response indicators are described to highlight the current clinical awareness of their use.