D
David E. Wildt
Researcher at Smithsonian Conservation Biology Institute
Publications - 422
Citations - 21321
David E. Wildt is an academic researcher from Smithsonian Conservation Biology Institute. The author has contributed to research in topics: Sperm & Sperm motility. The author has an hindex of 79, co-authored 420 publications receiving 19974 citations. Previous affiliations of David E. Wildt include Purdue University & Uniformed Services University of the Health Sciences.
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Journal ArticleDOI
Genetic basis for species vulnerability in the Cheetah
Stephen J. O'Brien,Melody E. Roelke,Laurie Marker,Amy Hauck Newman,Cheryl A. Winkler,D. G. Meltzer,L. Colly,James F. Evermann,Mitchell Bush,David E. Wildt +9 more
TL;DR: The extreme genetic monomorphism, especially at the major histocompatibility complex, and the apparent hypersensitivity of the cheetah to a viral pathogen may be related, provide a biological basis for understanding the adaptive significance of abundant genetic variation in outbred mammalian species.
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Genetic Restoration of the Florida Panther
Warren E. Johnson,David P. Onorato,Melody E. Roelke,E. Darrell Land,Mark W. Cunningham,Robert C. Belden,Roy McBride,Deborah Jansen,Mark Lotz,David B. Shindle,JoGayle Howard,David E. Wildt,Linda M. Penfold,Jeffrey A. Hostetler,Madan K. Oli,Stephen J. O'Brien +15 more
TL;DR: It is shown that panther numbers increased threefold, genetic heterozygosity doubled, survival and fitness measures improved, and inbreeding correlates declined significantly, although these results are encouraging, continued habitat loss, persistent inbreeding, infectious agents, and possible habitat saturation pose new dilemmas.
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Reproductive and genetic consequences of founding isolated lion populations
David E. Wildt,Mitchell Bush,K. L. Goodrowe,Craig Packer,Anne E. Pusey,Anne E. Pusey,Janine L. Brown,Janine L. Brown,P. Joslin,Stephen J. O'Brien,Stephen J. O'Brien +10 more
TL;DR: In an examination of three distinct lion populations, a direct correlation was observed between genetic variability and two physiological traits, incidence of abnormal sperm and circulating testosterone, a critical hormone for spermatogenesis.
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Comparative aspects of steroid hormone metabolism and ovarian activity in felids measured noninvasively in feces
Janine L. Brown,Samuel K. Wasser,Samuel K. Wasser,David E. Wildt,Laura H. Graham,Laura H. Graham +5 more
TL;DR: Noninvasive fecal assays were used to study steroid metabolism and ovarian activity in several felid species and indicated that steroid metabolism mechanisms appear to be conserved among these physically diverse, taxonomically related species.
Journal ArticleDOI
The cheetah is depauperate in genetic variation.
TL;DR: A sample of 55 South African cheetahs from two geographically isolated populations in South Africa were found to be genetically monomorphic at each of 47 allozyme (allelic isozyme) loci, significantly lower than levels of variation reported in other cats and mammals in general.