D
David F. Mark
Researcher at Cetus Corporation
Publications - 43
Citations - 5728
David F. Mark is an academic researcher from Cetus Corporation. The author has contributed to research in topics: Amino acid & Mutagenesis (molecular biology technique). The author has an hindex of 19, co-authored 43 publications receiving 5690 citations. Previous affiliations of David F. Mark include Stanford University.
Papers
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Journal ArticleDOI
Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping
TL;DR: Macrophages isolated from a wound site, and not exposed to cell culture conditions, expressed messenger RNA transcripts for TGF-alpha, T GF-beta, platelet-derived growth factor A-chain, and insulin-like growth factor-1 by a novel method for RNA analysis.
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Developmental Expression of PDGF, TGF-α , and TGF-β Genes in Preimplantation Mouse Embryos
TL;DR: The expression of a subset of growth factors in mouse blastocysts suggests a role for these factors in the growth and differentiation of early mammalian embryos.
Journal ArticleDOI
Molecular cloning of the complementary dna for human tumor necrosis factor
Alice M. Wang,Abla A. Creasey,M. B. Ladner,Leo S. Lin,James E. Strickler,JN Van Arsdell,R Yamamoto,David F. Mark +7 more
TL;DR: Human TNF was purified to apparent homogeneity as a 17.3-kilodalton protein from HL-60 leukemia cells and showed cytotoxic and cytostatic activities against various human tumor cell lines.
Journal ArticleDOI
Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)
Ernest S. Kawasaki,Martha B. Ladner,Alice M. Wang,Janelle N. Van Arsdell,M. Kim Warren,Mazie Y. Coyne,Vicki L. Schweickart,Mei-Ting Lee,Kenneth Wilson,Albert Boosman,E. Richard Stanley,Peter Ralph,David F. Mark +12 more
TL;DR: The CSF-1 appears to be encoded by a single-copy gene, but its expression results in the synthesis of several messenger RNA species, ranging in size from about 1.5 to 4.5 kilobases.
Patent
Human tumor necrosis factor
David F. Mark,Alice M. Wang,Martha B. Ladner,Abla A. Creasey,Leo S. Lin,Janelle N. Van Arsdell +5 more
TL;DR: In this article, a human tumor necrosis factor (TNF) was prepared using recombinant methods and a human promyelocytic leukemia cell line was induced using an improved induction procedure, and the TNF purified to homogeneity.