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David Feldman

Researcher at University of New South Wales

Publications -  469
Citations -  35066

David Feldman is an academic researcher from University of New South Wales. The author has contributed to research in topics: Calcitriol receptor & Vitamin D and neurology. The author has an hindex of 94, co-authored 457 publications receiving 33537 citations. Previous affiliations of David Feldman include Stanford University & University of California, San Francisco.

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The development of androgen-independent prostate cancer

TL;DR: It is predicted that understanding the pathways that lead to the development of androgen-independent prostate cancer will pave the way to effective therapies for these, at present, untreatable cancers.
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Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving

TL;DR: The findings raise the possibility that unsuspected estrogenic activity in the form of BPA may have an impact on experiments employing media autoclaved in polycarbonate flasks, and it remains to be determined whether BPA derived from consumer products manufactured from poly carbonate could significantly contribute to the pool of estrogenic substances in the environment.
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The role of vitamin D in reducing cancer risk and progression

TL;DR: Accumulating results from preclinical and some clinical studies strongly suggest that vitamin D deficiency increases the risk of developing cancer and that avoiding deficiency and adding vitamin D supplements might be an economical and safe way to reduce cancer incidence and improve cancer prognosis and outcome.
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Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.

TL;DR: The tissue and channel-type specificity and the directness and slow reversibility of the block are features that favor use of omega-conotoxin as a tool for purifying particular neuronal Ca2+ channels and defining their physiological function.
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1,25-dihydroxyvitamin D3 and malignant melanoma: the presence of receptors and inhibition of cell growth in culture.

TL;DR: The presence of specific, high-affinity receptors for 1,25-dihydroxyvitamin D3 in malignant melanoma is demonstrated and the first demonstration of a 1, 25-(OH)2D3 mediated action on tumor cells is demonstrated.