D
David L. Freedman
Researcher at Clemson University
Publications - 79
Citations - 2971
David L. Freedman is an academic researcher from Clemson University. The author has contributed to research in topics: Reductive dechlorination & Biodegradation. The author has an hindex of 28, co-authored 74 publications receiving 2697 citations. Previous affiliations of David L. Freedman include United States Environmental Protection Agency & University of Wisconsin–Milwaukee.
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Biological reductive dechlorination of tetrachloroethylene and trichloroethylene to ethylene under methanogenic conditions.
TL;DR: Studies with enrichment cultures of PCE- and TCE-degrading microorganisms provide evidence that, under methanogenic conditions, mixed cultures are able to completely dechlorinate PCE and T CE to ethylene, a product which is environmentally acceptable.
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Characterization of an isolate that uses vinyl chloride as a growth substrate under aerobic conditions.
TL;DR: It appears feasible to grow MF1 on a nontoxic substrate and then apply it to environments that do not exhibit a capacity for aerobic biodegradation of VC, suggesting that the predominant fate for VC is mineralization and incorporation into cell material.
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Comparative proteomics of Dehalococcoides spp. reveals strain-specific peptides associated with activity.
Robert M. Morris,Jennifer M. Fung,Brian G. Rahm,Sheng Zhang,David L. Freedman,Stephen H. Zinder,Ruth E. Richardson +6 more
TL;DR: This work identified RDase proteins that corresponded to known functions in four characterized cultures and predicted functions in an uncharacterized Dehalococcoides-containing mixed culture, and identified several additional proteins, including a formate dehydrogenase-like protein (Fdh), that had high coverage in all strains and under all growth conditions.
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Involvement of Linear Plasmids in Aerobic Biodegradation of Vinyl Chloride
TL;DR: Metabolism of VC and ethene by strains AJ and TD is initiated by an alkene monooxygenase, and this process occurs at many but not all sites where groundwater is contaminated with chloroethenes.
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Biodegradation of dichloromethane and its utilization as a growth substrate under methanogenic conditions.
TL;DR: Results suggested that nonmethanogenic organisms mediated DCM degradation, oxidizing a portion to CO2 and fermenting the remainder to acetate; acetate formation suggested involvement of an acetogen.