D
David M. Simpson
Researcher at Mount Sinai Hospital
Publications - 102
Citations - 6516
David M. Simpson is an academic researcher from Mount Sinai Hospital. The author has contributed to research in topics: Peripheral neuropathy & Polyneuropathy. The author has an hindex of 39, co-authored 102 publications receiving 6224 citations. Previous affiliations of David M. Simpson include Albert Einstein College of Medicine & Icahn School of Medicine at Mount Sinai.
Papers
More filters
Journal ArticleDOI
Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evidence-based review) Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
David M. Simpson,A. Blitzer,Allison Brashear,Cynthia L. Comella,Richard Dubinsky,Mark Hallett,Joseph Jankovic,Barbara I. Karp,Christy L. Ludlow,J. M. Miyasaki,M. Naumann,Yuen T. So +11 more
TL;DR: An evidence-based review of the safety and efficacy of botulinum neurotoxin in the treatment of adult and childhood spasticity found the highest quality literature available for the respective indications was as follows.
Journal ArticleDOI
Botulinum toxin type A in the treatment of upper extremity spasticity : A randomized, double-blind, placebo-controlled trial
David M. Simpson,D. N. Alexander,C. F. O'Brien,Michele Tagliati,A. S. Aswad,J. M. Leon,J. Gibson,J. M. Mordaunt,E. P. Monaghan +8 more
TL;DR: BTXA safely reduced upper extremity muscle tone in patients with chronic spasticity after stroke and reported significant improvement on the physician and patient Global Assessment of Response to Treatment at weeks 4 and 6 postinjection.
Journal ArticleDOI
Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy.
TL;DR: A placebo-controlled study of a high-concentration capsaicin dermal patch (NGX-4010) for the treatment of painful HIV-DSP suggests that NGX- 4010 could provide a promising new treatment for painful HIV neuropathy.
Journal ArticleDOI
Impact of Efavirenz on Neuropsychological Performance and Symptoms in HIV-Infected Individuals
David B. Clifford,Scott R. Evans,Yijun Yang,Edward P. Acosta,Karl Goodkin,Karen T. Tashima,David M. Simpson,David M. Dorfman,Heather J. Ribaudo,Roy M. Gulick +9 more
TL;DR: This investigator-initiated trial was a substudy of the AIDS Clinical Trials Group study A5095, a randomized, double-blind trial of 3 antiretroviral regimens: zidovudine and lamivudine in combination with efavirenz; abacvir; or abacavir and efvirenz in combination.
Journal ArticleDOI
Traditional pharmacological treatments for spasticity. Part II: General and regional treatments.
TL;DR: It appears preferable to use centrally acting drugs such as baclofen, tizanidine, and diazepam in spasticity of spinal origin (spinal cord injury and multiple sclerosis), whereas dantrolene sodium, due to its primary perpherial mechanism of action, may be preferable in spasticsity of cerebral origin (stroke and traumatic brain in jury).