D
David Sáez
Researcher at Carlos III Health Institute
Publications - 17
Citations - 722
David Sáez is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Klebsiella pneumoniae & Multilocus sequence typing. The author has an hindex of 13, co-authored 17 publications receiving 633 citations.
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Journal ArticleDOI
Emergence of OXA-48-producing Klebsiella pneumoniae and the novel carbapenemases OXA-244 and OXA-245 in Spain
Jesús Oteo,Juan Hernández,Mateu Espasa,Ana María Fleites,David Sáez,Verónica Bautista,María Pérez-Vázquez,Ma Dolores Fernández-García,Alberto Delgado-Iribarren,Isabel Sánchez-Romero,Luisa García-Picazo,Ma Dolores Miguel,Sonia Solís,E. Aznar,Gloria Trujillo,Concepción Mediavilla,D. Fontanals,Susana Rojo,Ana Vindel,José Campos +19 more
TL;DR: Multidrug-resistant K. pneumoniae producing OXA-48-like carbapenemase are emerging as important pathogens in Spain due to intra- and inter-hospital, clonal and non-clonal dissemination.
Journal ArticleDOI
Carbapenemase-Producing Enterobacteriaceae in Spain in 2012
Jesús Oteo,David Sáez,Verónica Bautista,Sara Fernández-Romero,Juan Manuel Hernández-Molina,María Pérez-Vázquez,Belén Aracil,José Campos +7 more
TL;DR: The number of CPE cases in Spain has increased sharply in recent years, due mainly to the emergence of OXA-48, and a limited number of multilocus sequence types and carbapenemase types were detected.
Journal ArticleDOI
Nosocomial Outbreak of VIM-1-Producing Klebsiella pneumoniae Isolates of Multilocus Sequence Type 15: Molecular Basis, Clinical Risk Factors, and Outcome
Isabel Sánchez-Romero,A. Asensio,Jesús Oteo,María Muñoz-Algarra,Beatriz Isidoro,Ana Vindel,José Álvarez-Avello,Bárbara Balandín-Moreno,Oscar Cuevas,Sara Fernández-Romero,Luisa Azañedo,David Sáez,José Campos +12 more
TL;DR: A high rate of associated mortality and great difficulty in controlling the spread of this clone, without permanent behavioral changes in the personnel, were observed.
Journal ArticleDOI
The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3
Jesús Oteo,María Pérez-Vázquez,Verónica Bautista,Adriana Ortega,Pilar Zamarrón,David Sáez,Sara Fernández-Romero,Noelia Lara,Raquel Ramiro,Belén Aracil,José Campos +10 more
TL;DR: KPC-producing Enterobacteriaceae isolates collected in Spain between 2012 and 2014 were analysed to identify the determinants of resistance and virulence and to de novo assemble the genome of one representative isolate of each of the three major K. pneumoniae clones detected.
Journal ArticleDOI
Emergence of NDM-producing Klebsiella pneumoniae and Escherichia coli in Spain: phylogeny, resistome, virulence and plasmids encoding blaNDM-like genes as determined by WGS.
María Pérez-Vázquez,Pedro J Sola Campoy,Adriana Ortega,Verónica Bautista,Sara Monzón,Guillermo Ruiz-Carrascoso,Guillermo Ruiz-Carrascoso,Jesús Mingorance,Jesús Mingorance,Eva Mª Gónzalez-Barberá,Concepción Gimeno,Belén Aracil,David Sáez,Noelia Lara,Sara Fernández,Juan José González-López,Juan José González-López,José Campos,Robert A. Kingsley,Robert A. Kingsley,Gordon Dougan,Jesús Oteo-Iglesias +21 more
TL;DR: The population structure of NDM-like-producing Klebsiella pneumoniae and Escherichia coli in Spain was elucidated and the plasmids harbouring blaNDM-like genes were determined.