D
David W. Hogg
Researcher at University of Toronto
Publications - 121
Citations - 29207
David W. Hogg is an academic researcher from University of Toronto. The author has contributed to research in topics: Melanoma & Germline mutation. The author has an hindex of 34, co-authored 113 publications receiving 25771 citations. Previous affiliations of David W. Hogg include University Health Network & Princess Margaret Cancer Centre.
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Patent
Diagnostic and therapeutic uses of SUFU gene
TL;DR: In this paper, the SUFU (supressor of fused) gene was identified as a tumor suppressor gene and mutations of SUFU gene were associated with the development of cancer, particularly medulloblastoma.
Journal ArticleDOI
Evaluation of low-dose CT scans for surveillance in stage I testicular cancer.
Peter Chung,Martin E. O’Malley,M. A. Jewett,Tony Panzarella,David W. Hogg,M. J. Moore,P. Bedard,Lynn Anson-Cartwright,B. Tew-George,Masoom A. Haider,Mary Gospodarowicz,Padraig Warde +11 more
TL;DR: Low dose CT scans may safely reduce radiation exposure due to retroperitoneal imaging during surveillance of stage I testicular cancer with minimal loss of diagnostic quality.
Journal ArticleDOI
Patterns of response to anti-PD1 treatment: Comparison of three radiological response criteria and effect on overall survival (OS) in metastatic melanoma patients (MM).
Minnie Kibiro,Leila Khoja,David W. Hogg,Marcus O. Butler,Ur Metser,Eshetu G. Atenafu,Anthony M. Joshua +6 more
TL;DR: Radiological assessment of patterns of response (R) to checkpoint inhibitors remain imperfect and irRC accounts for pseudoprogression but does not evaluate change in density.
Journal ArticleDOI
Phase III randomized, open-label, multicenter trial (BRIM3) comparing BRAF inhibitor RG7204 with dacarbazine in patients with V600E BRAF-mutated melanomas.
Paul B. Chapman,Axel Hauschild,C. Robert,James Larkin,J.B.A.G. Haanen,A. Ribas,David W. Hogg,Steven J. O'Day,Paolo A. Ascierto,Alessandro Testori,Paul Lorigan,R. Dummer,J. A. Sosman,Claus Garbe,Rebecca Lee,K. B. Nolop,B. Nelson,Jeannie Hou,Keith T. Flaherty,Grant A. McArthur +19 more
TL;DR: This data indicates thatatum-negative breast cancer cell reprograming is aogeneic and the BRCA1/BRCA2 “spatially distinct from other types of cancers” and may be a “window of opportunity” for further studies to explore the role of “cell reprogramming” in the immune response to chemotherapy.