D
David W. Holdsworth
Researcher at University of Western Ontario
Publications - 340
Citations - 10340
David W. Holdsworth is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Imaging phantom & Medicine. The author has an hindex of 54, co-authored 313 publications receiving 9522 citations. Previous affiliations of David W. Holdsworth include London Health Sciences Centre & University of Toronto.
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Journal Article
Image-based computational simulation of flow dynamics in a giant intracranial aneurysm.
TL;DR: Anatomic realism of lumen geometry and flow pulsatility is essential for elucidating the patient-specific nature of aneurysm hemodynamics and may be used to provide key hemodynamic information for prospective studies of anuerysm growth and rupture or to predict the response of an individual aneurYSm to therapeutic options.
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Micro-CT in small animal and specimen imaging
TL;DR: Micro-CT has the potential to replace serial histology as the reference standard in many in vitro studies, and provides a practical approach to obtain quantitative information during some longitudinal investigations in vivo.
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Characterization of common carotid artery blood-flow waveforms in normal human subjects
David W. Holdsworth,Chris J. D. Norley,Richard Frayne,David A. Steinman,David A. Steinman,Brian K. Rutt,Brian K. Rutt +6 more
TL;DR: It is proposed that realistic, pseudo-random flow waveform sequences can be generated for experimental studies by varying, from cycle to cycle, only T(RR) and V(CYC) of a single archetypal waveform.
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Characterization of volumetric flow rate waveforms in the normal internal carotid and vertebral arteries
TL;DR: Retrospectively gated phase contrast magnetic resonance imaging was used to measure time-resolved VFR waveforms from the two internal carotid arteries and two vertebral arteries of 17 young, normal volunteers, suggesting that the representative waveform shapes presented here may be used to characterize normal ICA and VA flow rate dynamics.
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In vivo small-animal imaging using micro-CT and digital subtraction angiography
TL;DR: It is shown that both methods can be used not only to provide morphological, but also functional information, such as cardiac function estimation or perfusion, in in vivo micro-computed tomography and digital subtraction angiography.