D
Debora B. Farber
Researcher at University of California, Los Angeles
Publications - 185
Citations - 7722
Debora B. Farber is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Gene & Retinal degeneration. The author has an hindex of 44, co-authored 184 publications receiving 7457 citations. Previous affiliations of Debora B. Farber include Jules Stein Eye Institute & University of California, San Diego.
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Journal ArticleDOI
Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase
Cathy Bowes,Tiansen Li,Michael Danciger,Michael Danciger,Leslie C. Baxter,Meredithe L. Applebury,Debora B. Farber +6 more
TL;DR: Evidence is presented that the candidate cDNA is the murine homologue of bovine phosphodiesterase β cDNA and that the mouse rd locus encodes the rod photoreceptor cGMP-phosphodiesterases β subunit.
Journal ArticleDOI
Transfer of microRNAs by embryonic stem cell microvesicles.
Alex Yuan,Erica L. Farber,A. Rapoport,Desiree Tejada,Roman Deniskin,N. B. Akhmedov,Debora B. Farber +6 more
TL;DR: In this paper, the authors characterized the RNA and protein content of embryonic stem cell microvesicles and showed that they can be engineered to carry exogenously expressed mRNA and protein such as green fluorescent protein (GFP).
Journal Article
Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles
TL;DR: The RNA and protein content of embryonic stem cell microvesicles are characterized and it is shown that they can be engineered to carry exogenously expressed mRNA and protein such as green fluorescent protein (GFP) and that these engineered microvesicle dock and fuse with other embryonic stem cells, transferring their GFP.
Journal Article
Estrogen receptor in the human eye: influence of gender and age on gene expression.
TL;DR: The presence of the ERalpha in the human eye suggests that the sex steroid hormone axis may play a role in the pathogenesis of certain ocular diseases.
Journal ArticleDOI
Rod-cone dysplasia in Irish setters: a defect in cyclic GMP metabolism in visual cells
TL;DR: An abnormality in retinal guanosine 3,5-monophosphate (cyclic GMP) metabolism is demonstrated in the inherited rod-cone dysplasis of Irish Setter dogs and may be characteristic of early-onset degenerative diseases of the retina.