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Deborah R. Leitner
Researcher at University of Graz
Publications - 25
Citations - 1516
Deborah R. Leitner is an academic researcher from University of Graz. The author has contributed to research in topics: Vibrio cholerae & Medicine. The author has an hindex of 13, co-authored 19 publications receiving 1055 citations.
Papers
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Journal ArticleDOI
Outer membrane vesicles as versatile tools for therapeutic approaches
TL;DR: A deeper understanding of immunoregulatory effects provoked by different outer membrane vesicles is the basis for their possible future applications ranging from inflammation and immune response modulation to anticancer therapy.
Book ChapterDOI
Biogenesis of Gram-Negative OMVs
TL;DR: This chapter discusses the observations resulting in the current models for OMV formation including their regulation and relevance for bacterial physiology and sheds some insights in the processes driving the liberation of OMVs from the bacterial surface.
Journal ArticleDOI
Efficacy and tolerability of alirocumab in Austrian clinical practice - results of the non-interventional PEARL-AT study.
Deborah R. Leitner,Hermann Toplak,Ludmilla Kedenko,Thomas Steinmaurer,Verena Gräff,Thomas Metzner,Elisabeth M Schwaiger,Rudolf Prager +7 more
TL;DR: Good overall efficacy of alirocumab in a real-world Austrian population is indicated, and safety was both in line with the clinical trial program as well as previous real- world observations.
Journal ArticleDOI
Nontoxigenic Vibrio cholerae Challenge Strains for Evaluating Vaccine Efficacy and Inferring Mechanisms of Protection
Bolutife Fakoya,Karthik Hullahalli,Daniel H. F. Rubin,Deborah R. Leitner,Roma Chilengi,David A. Sack,Matthew K. Waldor +6 more
TL;DR: Preclinical analyses presented here suggest that next-generation isogenic isogenic V. cholerae challenge strains derived from a contemporary Zambian clinical isolate have the potential to enhance the safety, relevance, and scope of future cholera vaccine challenge studies and be valuable reagents for studies of immunity to cholERA.
letters-and-commentsDOI
Reemergence of Cholera in Haiti
Daniel H. F. Rubin,Franz G. Zingl,Deborah R. Leitner,Ralph Ternier,Valusnor Compère,Samson Marseille,Damien Slater,Jason B. Harris,Fahima Chowdhury,Firdausi Qadri,Jacques Boncy,Louise C. Ivers,Matthew K. Waldor +12 more
TL;DR: In this article , the authors present genomic and phenotypic analysis of the Vibrio cholerae isolated from a stool sample collected on September 30th, 2022 of an index case, a 10-year-old girl who presented with watery diarrhea and severe dehydration.