D
Dejan Šemrov
Researcher at University of Ljubljana
Publications - 10
Citations - 1064
Dejan Šemrov is an academic researcher from University of Ljubljana. The author has contributed to research in topics: Electrochemotherapy & Finite element method. The author has an hindex of 9, co-authored 10 publications receiving 1015 citations.
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A validated model of in vivo electric field distribution in tissues for electrochemotherapy and for DNA electrotransfer for gene therapy.
TL;DR: The maximum of induced transmembrane potential difference in a single cell of the rabbit liver tissue can be estimated to be 394+/-75 and 694+/-136 mV, respectively, for reversible and irreversible electroporation threshold.
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The Importance of Electric Field Distribution for Effective in Vivo Electroporation of Tissues
TL;DR: The results of this study clearly demonstrate that numerical model is reliable and can be very useful in the additional search for electrodes that would make electrochemotherapy and in vivo electroporation in general more efficient and shows that better coverage of tumors with sufficiently high electric field is necessary for improved effectiveness of electroChemotherapy.
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Electric Field-Induced Transmembrane Potential Depends on Cell Density and Organizatio
TL;DR: This study examines how electric fields interact with and polarize a system of cells and considers how cell density and organization impact on induced cell transmembrane potential due to an external electric field.
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Changing electrode orientation improves the efficacy of electrochemotherapy of solid tumors in mice
TL;DR: Changing of the electrode orientation resulted in improved anti-tumor efficacy of the electrochemotherapy: prolonged tumor growth delay and higher percentage of short and long term complete responses of the tumors.
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Calculation of the electrical parameters in electrochemotherapy of solid tumours in mice
Dejan Šemrov,Damijan Miklavčič +1 more
TL;DR: It is concluded that changing electrode orientation strongly influences the distribution of the electric field inside the tumour in the electrochemotherapy of solid tumours in mice, which is in good agreement with the results of the experimental study.