Denae Nash

TL;DR: The lumefantrine plasma concentration profile is the main determinant of efficacy of artemether-lumefanrine in patients with uncomplicated Plasmodium falciparum malaria and, therefore, treatment responses when plasma lumfantrine levels are subtherapeutic.

TL;DR: An example of such a "soft" selective sweep in the malaria parasite Plasmodium falciparum that involves adaptive genome rearrangements is described and statistical methods based on diversity reduction may be inefficient at detecting evidence for selection in genome-wide marker screens.

TL;DR: Comparing microsatellite variation around two drug resistance genes in malaria parasite populations exposed to strong or weak selection by anti-malarial drugs demonstrates that different realizations of the same selective sweeps may vary considerably in size and shape, in a manner broadly consistent with selection history.

TL;DR: The true magnitude of NYCs BA.12.2/BA.2.1 surge was vastly underestimated by routine SARS-CoV-2 surveillance, and representative surveys are needed for timely surge detection, and to estimate the true burden of infection, hybrid protection, and uptake of time-sensitive treatments.

TL;DR: To increase vaccination coverage among young children, vaccination campaigns should focus on both vaccinated and unvaccinated parents and messaging should be specific to the child's age.