D
Denise Thomson
Researcher at University of Alberta
Publications - 38
Citations - 1098
Denise Thomson is an academic researcher from University of Alberta. The author has contributed to research in topics: Systematic review & Randomized controlled trial. The author has an hindex of 13, co-authored 33 publications receiving 910 citations. Previous affiliations of Denise Thomson include Cochrane Collaboration.
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Journal ArticleDOI
Standard 6: Age Groups for Pediatric Trials
Katrina Williams,Denise Thomson,Iva Seto,Despina G. Contopoulos-Ioannidis,John P. A. Ioannidis,Sarah Curtis,Evelyn Constantin,Gitanjali Batmanabane,Lisa Hartling,Terry P. Klassen +9 more
TL;DR: In this study, 128 meta-analyses from Cochrane reviews, containing data on at least 1 adult and 1 pediatric randomized controlled trial (RCT) with a binary primary efficacy outcome, were reviewed and it was found that in all except 1 case, the 95% confidence intervals could not exclude a relative difference in treatment efficacy between adults and children of >20%.
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A Descriptive Analysis of Overviews of Reviews Published between 2000 and 2011
TL;DR: There is a need for methodological rigor and consistency in overviews, as well as empirical evidence to support the methods employed, and considerable variation in the methods used for overviews is shown.
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The evolution of a new publication type: Steps and challenges of producing overviews of reviews.
TL;DR: Some of the logistical and methodological challenges of producing overviews of reviews are highlighted, including identification of the research question, establishment of the author team, selection of outcomes and included SRs, and presentation of findings.
Central Questions of Anonymization: A Case Study of Secondary Use of Qualitative Data
TL;DR: This case study is proposed to present a case study of working with anonymized data on the research project, Knowledge Utilization and Policy Implementation, a five-year program funded by the Canadian Institutes of Health Research.
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Controlled trials in children: quantity, methodological quality and descriptive characteristics of pediatric controlled trials published 1948-2006.
TL;DR: The quantity and quality of pediatric controlled trials has increased over time; however, much work remains to be done, particularly in improving methodological issues around conduct and reporting of trials.