D
Denitsa Momekova
Researcher at Sofia Medical University
Publications - 70
Citations - 1263
Denitsa Momekova is an academic researcher from Sofia Medical University. The author has contributed to research in topics: Mesoporous silica & Drug delivery. The author has an hindex of 16, co-authored 65 publications receiving 955 citations.
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Journal ArticleDOI
The effect of the water on the curcumin tautomerism: A quantitative approach
TL;DR: In this paper, the tautomerism of curcumin has been investigated in ethanol/water binary mixtures by using UV-Vis spectroscopy and advanced quantum-chemical calculations.
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Ivermectin as a potential COVID-19 treatment from the pharmacokinetic point of view: antiviral levels are not likely attainable with known dosing regimens
Georgi Momekov,Denitsa Momekova +1 more
TL;DR: The available pharmacokinetic data from clinically relevant and excessive dosing studies indicate that the SARS-CoV-2 inhibitory concentrations are not likely to be attainable in humans.
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Anticancer Potencies of PtII‐ and PdII‐linked M2L4 Coordination Capsules with Improved Selectivity
Anife Ahmedova,Denitsa Momekova,Masahiro Yamashina,Pavletta Shestakova,Georgi Momekov,Munetaka Akita,Michito Yoshizawa +6 more
TL;DR: Pt(II) - and Pd(II)-linked M2 L4 coordination capsules, providing a confined cavity encircled by polyaromatic frameworks, exhibit anticancer activities superior to cisplatin against two types of leukemic cells and pronounced toxicity against cisplasin-resistant cells.
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Design and in vitro evaluation of doxycycline hyclate niosomes as a potential ocular delivery system
TL;DR: Findings indicate that niosomes could be considered as a plausible drug delivery platform for for ophthalmic application of doxycycline.
Journal ArticleDOI
Long-circulating, pH-sensitive liposomes sterically stabilized by copolymers bearing short blocks of lipid-mimetic units.
Denitsa Momekova,Stanislav Rangelov,Stanislav Yanev,Elena Nikolova,Spiro Konstantinov,Birgit Romberg,Gert Storm,Nikolay Lambov +7 more
TL;DR: The juxtaposition of the blood clearance curves and the calculated pharmacokinetic parameters show that the block copolymer confers superior longevity in vivo, and can be consider as promising sterically stabilizing agents for pH-sensitive liposomes.