Dennis D. Heath

TL;DR: Data indicate that the dienone bridge present in curcumin, but not in TC, is necessary to reduce plaque deposition and protein oxidation in an Alzheimer's model, and should help translation efforts from multiple successful preclinical models.

TL;DR: Curcumin was generally well-tolerated although three subjects on curcumin withdrew due to gastrointestinal symptoms, and preliminary data suggest limited bioavailability of this compound.

TL;DR: TheCurcumin content of these seasoning products that are consumed as a component of the diet should be considered in evaluating baseline tissue concentration and response to curcumin supplementation, which is under study in chemoprevention trials.

TL;DR: Chronic hyperglycemia is statistically significantly associated with reduced overall survival in survivors of early-stage breast cancer and further study of diabetes and its relationship to breast cancer outcomes is warranted.

TL;DR: In this article, the authors developed a robust automated analytical method for the determination of curcumin in plasma and urine, which is used extensively in the food industry and is a major component of curry powder.