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Bruce Teter
Researcher at University of California, Los Angeles
Publications - 45
Citations - 6131
Bruce Teter is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Apolipoprotein E & Alzheimer's disease. The author has an hindex of 28, co-authored 44 publications receiving 5768 citations. Previous affiliations of Bruce Teter include University of Southern California & Veterans Health Administration.
Papers
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Journal ArticleDOI
Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer's Disease
Giselle P. Lim,Giselle P. Lim,Fusheng Yang,Fusheng Yang,T. Chu,T. Chu,Patrick B. Chen,Patrick B. Chen,Walter Beech,Walter Beech,Bruce Teter,Bruce Teter,Tracy S. Tran,Tracy S. Tran,Oliver J. Ubeda,Oliver J. Ubeda,K. Hsiao Ashe,Sally A. Frautschy,Greg M. Cole +18 more
TL;DR: The anti-inflammatory drug ibuprofen, which has been associated with reduced AD risk in human epidemiological studies, can significantly delay some forms of AD pathology, including amyloid deposition, when administered early in the disease course of a transgenic mouse model of AD.
Journal ArticleDOI
Docosahexaenoic Acid Protects from Dendritic Pathology in an Alzheimer's Disease Mouse Model
Frédéric Calon,Giselle P. Lim,Giselle P. Lim,Fusheng Yang,Fusheng Yang,Takashi Morihara,Takashi Morihara,Bruce Teter,Bruce Teter,Oliver J. Ubeda,Oliver J. Ubeda,Phillippe Rostaing,Antoine Triller,Norman Salem,Karen H. Ashe,Sally A. Frautschy,Sally A. Frautschy,Greg M. Cole,Greg M. Cole +18 more
TL;DR: Reduction of dietary n-3 PFA in an AD mouse model resulted in 80%-90% losses of the p85alpha subunit of phosphatidylinositol 3-kinase and the postsynaptic actin-regulating protein drebrin, as in AD brain.
Journal ArticleDOI
A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.
Giselle P. Lim,Frédéric Calon,Takashi Morihara,Fusheng Yang,Bruce Teter,Oliver J. Ubeda,Norman Salem,Sally A. Frautschy,Greg M. Cole +8 more
TL;DR: DHA modulated APP processing by decreasing both α- and β-APP C-terminal fragment products and full-length APP, which suggests DHA could be protective against β-amyloid production, accumulation, and potential downstream toxicity.
Journal ArticleDOI
Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease
Aynun N. Begum,Mychica Jones,Giselle P. Lim,Takashi Morihara,Peter Kim,Dennis D. Heath,Cheryl L. Rock,Mila A. Pruitt,Fusheng Yang,Beverly Hudspeth,Shuxin Hu,Kym F. Faull,Bruce Teter,Greg M. Cole,Sally A. Frautschy +14 more
TL;DR: Data indicate that the dienone bridge present in curcumin, but not in TC, is necessary to reduce plaque deposition and protein oxidation in an Alzheimer's model, and should help translation efforts from multiple successful preclinical models.
Book ChapterDOI
Neuroprotective effects of curcumin
TL;DR: Accumulating cell culture and animal model data show that dietary curcumin is a strong candidate for use in the prevention or treatment of major disabling age-related neurodegenerative diseases like Alzheimer's, Parkinson's, and stroke.