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Dennis K. Yue

Researcher at University of Sydney

Publications -  191
Citations -  10330

Dennis K. Yue is an academic researcher from University of Sydney. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 52, co-authored 190 publications receiving 9625 citations. Previous affiliations of Dennis K. Yue include Royal Prince Alfred Hospital & Allied Hospital.

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Diabetes Control and Complications Trial. Position statement of the Australian Diabetes Society.

TL;DR: Analysis of the data does not support the existence of a specific target value for HbA1c at which the benefits of intensive therapy are maximised and the risks minimised, and the position of the Australian Diabetes Society is as follows.
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Impaired vascular reactivity in insulin-dependent diabetes mellitus is related to disease duration and low density lipoprotein cholesterol levels

TL;DR: Vascular reactivity is impaired in the systemic arteries of asymptomatic young adults with insulin-dependent diabetes and may represent early large-vessel disease, and these patients appear particularly vulnerable to damage from LDL cholesterol, even at levels considered acceptable in nondiabetic subjects.
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Increased matrix metalloproteinase-9 predicts poor wound healing in diabetic foot ulcers.

TL;DR: Findings suggest that a milieu with high MMP-9 may be indicative of inflammation and poor wound healing, andMeasurements of M MP-9, TIMP-1, and TGF-ß in wound fluid may help to identify ulcers at risk of poor healing.
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Long-Term Complications and Mortality in Young-Onset Diabetes: Type 2 diabetes is more hazardous and lethal than type 1 diabetes

TL;DR: Young-onset T2DM is the more lethal phenotype of diabetes and is associated with a greater mortality, more diabetes complications, and unfavorable cardiovascular disease risk factors when compared with T1DM.