D
Derek R. MacFadden
Researcher at Ottawa Hospital Research Institute
Publications - 118
Citations - 3523
Derek R. MacFadden is an academic researcher from Ottawa Hospital Research Institute. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 21, co-authored 89 publications receiving 1854 citations. Previous affiliations of Derek R. MacFadden include University of Toronto & Harvard University.
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Journal ArticleDOI
Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis.
Bradley J Langford,Miranda So,Miranda So,Miranda So,Sumit Raybardhan,Valerie Leung,Duncan Westwood,Derek R. MacFadden,Jean-Paul R. Soucy,Nick Daneman +9 more
TL;DR: To determine the prevalence of bacterial co-infection and secondary infection in patients with confirmed COVID-19, a systematic search of MEDLINE, OVID Epub and EMBASE databases for English language literature from 2019 to April 16, 2020 was performed.
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Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis.
Bradley J Langford,Miranda So,Miranda So,Miranda So,Sumit Raybardhan,Valerie Leung,Jean-Paul R. Soucy,Duncan Westwood,Nick Daneman,Derek R. MacFadden +9 more
TL;DR: In this paper, the prevalence and associated factors of antibiotic prescribing in patients with SARS-CoV-2 infection were estimated in a randomized controlled trial with 30,623 patients.
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Antibiotic resistance increases with local temperature
Derek R. MacFadden,Sarah F. McGough,David N. Fisman,Mauricio Santillana,John S. Brownstein,John S. Brownstein +5 more
TL;DR: The findings suggest that current forecasts of the burden of antibiotic resistance could be significant underestimates in the face of a growing population and climate change4.
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Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak
Isaac I. Bogoch,Isaac I. Bogoch,Maria I. Creatore,Martin S. Cetron,John S. Brownstein,John S. Brownstein,Nicki Pesik,Jennifer Miniota,Theresa Tam,Wei Hu,Adriano Nicolucci,Saad Ahmed,James W Yoon,Isha Berry,Simon I. Hay,Simon I. Hay,Aranka Anema,Aranka Anema,Andrew J. Tatem,Andrew J. Tatem,Derek R. MacFadden,Matthew German,Kamran Khan,Kamran Khan +23 more
TL;DR: Assessment of the potential for Ebola virus to spread across international borders via commercial air travel and the relative efficiency of exit versus entry screening of travellers at commercial airports finds exit screening at airports in Guinea, Liberia, and Sierra Leone would be the most efficient frontier at which to assess the health status of traveller at risk of Ebola virus exposure.
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Impact of Reported Beta-Lactam Allergy on Inpatient Outcomes: A Multicenter Prospective Cohort Study
Derek R. MacFadden,Anthony LaDelfa,Jessica Leen,Wayne L. Gold,Nick Daneman,Elizabeth A Weber,Ibrahim Al-Busaidi,Dan Petrescu,Ilana S Saltzman,Megan Devlin,Nisha Andany,Jerome A. Leis +11 more
TL;DR: Avoidance of preferred beta-lactam therapy in patients who report allergy is associated with an increased risk of adverse events, and development of inpatient programs aimed at accurately identifying beta-Lactam allergies to safely promote beta- lactam administration among these patients is warranted.