D
Desai Radhika Chetan
Publications - 2
Citations - 434
Desai Radhika Chetan is an academic researcher. The author has contributed to research in topics: Gamma delta T cell & Neuroendocrine tumors. The author has an hindex of 1, co-authored 2 publications receiving 345 citations.
Papers
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Journal ArticleDOI
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
Laura Saunders,Alexander J. Bankovich,Wade C. Anderson,Monette Aujay,Sheila Bheddah,KristenAnn Black,Desai Radhika Chetan,Paul Anthony Escarpe,Johannes Hampl,Amy Laysang,David R. Liu,Javier Lopez-Molina,Milly Milton,Albert Park,Marybeth A. Pysz,Hui Shao,Brian Slingerland,Torgov Michael,Samuel A. Williams,Orit Foord,Howard Philip Wilson,Jacek Jassem,Andrzej Badzio,Piotr Czapiewski,David H. Harpole,Afshin Dowlati,Pierre P. Massion,William D. Travis,M. Catherine Pietanza,M. Catherine Pietanza,John T. Poirier,John T. Poirier,Charles M. Rudin,Robert A. Stull,Scott J. Dylla +34 more
TL;DR: The authors targeted DLL3 with an antibody conjugated to a cytotoxic drug, which proved to be much more effective than standard chemotherapy for treating patient-derived tumor xenografts and is a promising first-in-class ADC for the treatment of high-grade pulmonary neuroendocrine tumors.
Patent
Methods for selective expansion of gamma delta t-cell populations and compositions thereof
Aya Jakobovits,Foord Orit,Andy An-deh Lin,Marianne Santaguida,Desai Radhika Chetan,Jing Yifeng Frank,Daulet Kadyl Satpayev,Li Yan +7 more
TL;DR: In this article, the authors present methods for the selective expansion of γδ T-cell population(s), compositions and ad-mixtures thereof and methods for using the same as a therapeutic.