J
Javier Lopez-Molina
Publications - 3
Citations - 443
Javier Lopez-Molina is an academic researcher. The author has contributed to research in topics: Neuroendocrine tumors & Pulmonary neuroendocrine tumor. The author has an hindex of 2, co-authored 3 publications receiving 354 citations.
Papers
More filters
Journal ArticleDOI
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
Laura Saunders,Alexander J. Bankovich,Wade C. Anderson,Monette Aujay,Sheila Bheddah,KristenAnn Black,Desai Radhika Chetan,Paul Anthony Escarpe,Johannes Hampl,Amy Laysang,David R. Liu,Javier Lopez-Molina,Milly Milton,Albert Park,Marybeth A. Pysz,Hui Shao,Brian Slingerland,Torgov Michael,Samuel A. Williams,Orit Foord,Howard Philip Wilson,Jacek Jassem,Andrzej Badzio,Piotr Czapiewski,David H. Harpole,Afshin Dowlati,Pierre P. Massion,William D. Travis,M. Catherine Pietanza,M. Catherine Pietanza,John T. Poirier,John T. Poirier,Charles M. Rudin,Robert A. Stull,Scott J. Dylla +34 more
TL;DR: The authors targeted DLL3 with an antibody conjugated to a cytotoxic drug, which proved to be much more effective than standard chemotherapy for treating patient-derived tumor xenografts and is a promising first-in-class ADC for the treatment of high-grade pulmonary neuroendocrine tumors.