D
Désirée van der Heijde
Researcher at Leiden University Medical Center
Publications - 764
Citations - 57315
Désirée van der Heijde is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Ankylosing spondylitis & Medicine. The author has an hindex of 107, co-authored 674 publications receiving 48488 citations. Previous affiliations of Désirée van der Heijde include Leiden University & Radboud University Nijmegen.
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Journal ArticleDOI
Treatment of gout patients with impairment of renal function: a systematic literature review.
Irene van Echteld,Caroline van Durme,Louise Falzon,Robert B. Landewé,Désirée van der Heijde,Daniel Aletaha +5 more
TL;DR: In gout patients with renal insufficiency febuxostat, rasburicase, benzbromarone, and allopurinol + benzbomarone seemed to be effective and safe; allopURinol may be cautiously titrated until the target uric acid level has been reached, and may improve renal function.
Journal ArticleDOI
Existing joint erosions increase the risk of joint space narrowing independently of clinical synovitis in patients with early rheumatoid arthritis
Robert Landewé,Josef S Smolen,Stefan Florentinus,Su Chen,Benoît Guérette,Désirée van der Heijde +5 more
TL;DR: Existing JE predisposes individual joints to development of JSN independently of synovitis in the same joint, and treatment with ADA + MTX prevents JE/JSN progression independently of its ability to suppresssynovitis and limits JE-JSN onset and progression in joints with existing damage.
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Facet joint ankylosis in r-axSpA: detection and 2-year progression on whole spine low-dose CT and comparison with syndesmophyte progression
Rosalinde Stal,Floris A. van Gaalen,Alexandre Sepriano,Alexandre Sepriano,Juergen Braun,Monique Reijnierse,Rosaline van den Berg,Désirée van der Heijde,Xenofon Baraliakos +8 more
TL;DR: Assessing facet joints in addition to syndesmophytes detected substantially more patients with damage progression over two years than previous studies evaluating facet joints by ldCT in r-axSpA.
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Hierarchy of Impairment of Spinal Mobility Measures in Ankylosing Spondylitis: Twelve-Year Data
Sofia Ramiro,Robert Landewé,Désirée van der Heijde,Carmen Stolwijk,Maxime Dougados,Filip Van den Bosch,Astrid van Tubergen +6 more
TL;DR: In this paper, the authors investigated which spinal mobility measures (SMMs) are most frequently impaired in patients with ankylosing spondylitis and whether assessing fewer measures sufficiently captures impairment in spinal mobility.
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Uncovering the heterogeneity of disease impact in axial spondyloarthritis: bivariate trajectories of disease activity and quality of life
Maike S. V. Imkamp,Valéria Lima Passos,Annelies Boonen,Suzanne Arends,Maxime Dougados,Robert Landewé,Sofia Ramiro,Filip Van den Bosch,Désirée van der Heijde,F. Wink,Anneke Spoorenberg,Astrid van Tubergen +11 more
TL;DR: The profiles revealed that both individual-related and disease-related features define the type of disease course in respect to HRQoL and disease activity in axSpA, and may provide clinicians insight into the differences among patients and help in the management of the disease.