Devashish Sengupta

TL;DR: In this article, 1-Aryl-2-phenyl-(methylthio) -4-dimethylamino-1, 3-butadienes 1 gave different pyrimidones with different haloketenes (chloro, bromo and iodo).

TL;DR: This is the first report demonstrating the dual activity of nitroporphyrin-zinc complexes as antiviral and anti-cancer, which will aid in their development as therapeutics in clinics.

TL;DR: The DFT calculations of the singlet-triplet energy gap (ΔE) of all the four hydrophilic thiophenium porphyrin derivatives establish the potential applicability of these cationic photosensitizers as PDT agents.

TL;DR: It was found that B.3, having a pyridinium group attached to the meso-position of the macrocycle along with three distal cationic pyrinium groups, independent of the porphyrinic electron delocalisation cycle, showed better photocytotoxic efficacy and higher potential to promote apoptosis and hence better efficacy as PS towards cancer photodynamic therapy (PDT).

TL;DR: In this paper, the cis-A2B2 type porphyrin derivative, synthesized by replacing two p-hydroxyphenyl groups at the meso-positions with two pnitrophenyl moieties, 5,10-bis-(4-oxymethyl)-15,20-bis-porphyrin PN2(OH)2 and its zinc(II) 2Zn have more promising photosensitizing and photobiological activities.