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Di Zhang

Researcher at University of Pittsburgh

Publications -  8
Citations -  893

Di Zhang is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: KRAS & Minimal clinically important difference. The author has an hindex of 7, co-authored 8 publications receiving 644 citations.

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Comparative Effectiveness of Thermal Ablation, Surgical Resection, and Active Surveillance for T1a Renal Cell Carcinoma: A Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked Population Study.

TL;DR: For T1aN0M0 RCC, TA confers cancer-specific survival and OS similar to those seen with surgical management, with significantly fewer adverse outcomes at 1 year after the procedure and similar rates of secondary cancer events compared with surgery.
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KRAS Status as an Independent Prognostic Factor for Survival after Yttrium-90 Radioembolization Therapy for Unresectable Colorectal Cancer Liver Metastases.

TL;DR: Patients with CRC and KRAS wt may derive greater survival benefit from (90)Y radioembolization therapy than patients with KRAS mutant, andMultivariate Cox regression analysis demonstrated Child-Pugh class, CEA, and KRas status to be independent prognostic factors for OS, even when correcting for the effect of chemotherapy after (90).
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Meta-analysis: adjusted indirect comparison of drug-eluting bead transarterial chemoembolization versus 90 Y-radioembolization for hepatocellular carcinoma

TL;DR: This meta-analysis shows greater 1-year survival benefit for DEB-TACE over 90Y-radioembolization, which has a favourable 2- & 3- year survival benefit trend over90Y- RadioEmbolization.
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Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90

TL;DR: Longer PFS is associated with KRAS wt vs. mut following SIRT Y90, and only KRas wt was an independent prognostic factor for longer PFS in multivariate analysis.