D
Diederick Stoffers
Researcher at Netherlands Institute for Neuroscience
Publications - 62
Citations - 4281
Diederick Stoffers is an academic researcher from Netherlands Institute for Neuroscience. The author has contributed to research in topics: Parkinson's disease & Resting state fMRI. The author has an hindex of 32, co-authored 62 publications receiving 3647 citations. Previous affiliations of Diederick Stoffers include VU University Medical Center & VU University Amsterdam.
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Journal ArticleDOI
Idiopathic hyposmia as a preclinical sign of Parkinson's disease
Mirthe M. Ponsen,Diederick Stoffers,Diederick Stoffers,Jan Booij,Berthe L. F. van Eck-Smit,Erik Ch. Wolters,Henk W. Berendse +6 more
TL;DR: Results indicate that idiopathic olfactory dysfunction is associated with an increased risk of developing PD of at least 10%.
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Cognitive dysfunction and dementia in Parkinson's disease.
TL;DR: Dementia in PD is typically characterized by a progressive dysexecutive syndrome with attentional deficits and fluctuating cognition, often accompanied by psychotic symptoms, thought to be the result of a combination of both subcortical and cortical changes.
Journal ArticleDOI
Slowing of oscillatory brain activity is a stable characteristic of Parkinson's disease without dementia
Diederick Stoffers,J.L.W. Bosboom,Jan Berend Deijen,Erik Ch. Wolters,Henk W. Berendse,Cornelis J. Stam +5 more
TL;DR: Widespread slowing of oscillatory brain activity is a characteristic of non-demented Parkinson's disease patients from the earliest clinical stages onwards that is (largely) independent of disease duration, stage and severity and hardly influenced by dopaminomimetic treatment.
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Disrupted brain network topology in Parkinson's disease: a longitudinal magnetoencephalography study.
Kim T. E. Olde Dubbelink,Arjan Hillebrand,Diederick Stoffers,Jan Berend Deijen,Jos W. R. Twisk,Cornelis J. Stam,Henk W. Berendse +6 more
TL;DR: It is observed that brain networks in early stage untreated patients displayed lower local clustering with preserved path length in the delta frequency band in comparison to controls, and impaired local efficiency and network decentralization are very early features of Parkinson's disease that continue to progress over time.
Journal ArticleDOI
Increased cortico-cortical functional connectivity in early-stage Parkinson's disease: an MEG study.
Diederick Stoffers,J.L.W. Bosboom,Jan Berend Deijen,E.Ch. Wolters,Cornelis J. Stam,Henk W. Berendse +5 more
TL;DR: Increased resting-state cortico-cortical functional connectivity in the 8-10 Hz alpha range is a feature of PD from the earliest clinical stages onward and may be linked to the topographical progression of pathology over the brain.