Diego Rafael Uñates

TL;DR: The finding proposes a molecular mechanism which contributes to the understanding of the signal transduction pathway that takes place in a physiological process as chemotaxis, and is integrated into the pharmacological inhibition of signaling molecules, measurements of the concentrations of second messengers and activation of the chemotactic signaling.

TL;DR: It is concluded that only the CU but not the oocyte secretes P, and the latter chemoattract spermatozoa by means of a cell surface receptor, which may be of interest in assisted reproduction procedures in humans, animals of economic importance and endangered species.

TL;DR: A method to recruit spermatozoa at the best functional state, based on sperm guidance toward progesterone, is developed, which supplies a sperm population enriched with spermatozosa at an optimum physiological state that may improve the assisted reproductive technology outcome.

TL;DR: The results suggest that spermatozoa are transported to and retained at the fertilization site by the combined action of a chemical guidance and the oviduct movement.

TL;DR: This study characterizes the pattern of movement of human spermatozoa during chemotactic re-orientation towards a progesterone source, which is a physiological attractant candidate and may be used to identify the few cells that are undergoing chemotaxis at a given time.