D
Dieter Pöhlau
Researcher at Centre Hospitalier Universitaire de Toulouse
Publications - 4
Citations - 529
Dieter Pöhlau is an academic researcher from Centre Hospitalier Universitaire de Toulouse. The author has contributed to research in topics: Multiple sclerosis & Interleukin 21. The author has an hindex of 2, co-authored 4 publications receiving 517 citations.
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Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo- controlled, randomized phase II trial
Ludwig Kappos,Giancarlo Comi,Hillel Panitch,Joel Oger,Jack P. Antel,Paul J. Conlon,Lawrence Steinman,Alexander Rae-Grant,John Castaldo,Nancy Eckert,Joseph Guarnaccia,Pamela Mills,Gary Johnson,Peter A. Calabresi,Carlo Pozzilli,Stefano Bastianello,Elisabetta Giugni,Tatiana Witjas,Patrick J. Cozzone,Jean Pelletier,Dieter Pöhlau,Horst Przuntek,Volker Hoffmann,Christopher T. Bever,Eleanor Katz,Michel Clanet,Isabelle Berry,David Brassat,Irene Brunet,Gilles Edan,Pierre Duquette,Ernst Wilhelm Radue,Dagmar Schött,Carmen Lienert,Alice Taksaoui,M. Rodegher,Massimo Filippi,Alan C. Evans,Pierre Bourgouin,Alex P. Zijdenbos,Shawki Salem,Nicholas Ling,David G. Alleva,Eric B. Johnson,Amitabh Gaur,Paul D. Crowe,Xin-Jun Liu +46 more
TL;DR: There were no increases in either clinical relapses or in new enhancing lesions in any patient, even those with hypersensitivity reactions, and secondary analysis showed that the volume and number of enhancing lesions were reduced at a dose of 5 mg.
Journal ArticleDOI
Induction of apoptosis of CD4+ T cells by immunomodulatory therapy of multiple sclerosis with glatiramer acetate
M. Rieks,Volker Hoffmann,Orhan Aktas,Miriam Juschka,Iris Spitzer,Nils Brune,Sebastian Schimrigk,Horst Przuntek,Dieter Pöhlau +8 more
TL;DR: Analysis of blood samples obtained every 6 weeks showed an increase in apoptotic T helper cells after 30 weeks of therapy, suggesting that GA-mediated immunomodulation might involve the apoptotic elimination of T helpers.