Organic Chemistry By Dr. I. L. Finar. Vol. 2: Stereochemistry and the Chemistry of Natural Products. Pp. xi + 733. (London and New York: Longmans, Green and Co., Ltd., 1956.) 40s. net.

Advanced Organic Chemistry

Stereoselective Addition to N-Activated Pyridines James A. Bull,‡ James J. Mousseau, Guillaume Pelletier,† and Andre ́ B. Charette*,† †Department of Chemistry, Universite ́ de Montreál, P.O. Box 6128, Station Downtown, Montreál, Queb́ec, Canada H3C 3J7 ‡Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, U.K. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA

Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition to N-Activated Pyridines

Heterogeneous Catalysts for the One-Pot Synthesis of Chemicals and Fine Chemicals

Azobenzenes are ubiquitous motifs very important in many areas of science. Azo compounds display crucial properties for important applications, mainly for the chemical industry. Because of their discovery, the main application of aromatic azo compounds has been their use as dyes. These compounds are excellent candidates to function as molecular switches because of their efficient cis–transisomerization in the presence of appropriate radiation. The classical methods for the synthesis of azo compounds are the azo coupling reaction (coupling of diazonium salts with activated aromatic compounds), the Mills reaction (reaction between aromatic nitroso derivatives and anilines) and the Wallach reaction (transformation of azoxybenzenes into 4-hydroxy substituted azoderivatives in acid media). More recently, other preparative methods have been reported. This critical review covers the various synthetic methods reported on azo compounds with special emphasis on the more recent ones and their mechanistic aspects (170 references).

http://www.chtf.stuba.sk/~szolcsanyi/education/files/Organicka%20chemia%20II/Prednaska%202_Aminy_Reakcie/Doplnkove%20studijne%20materialy/Azobenzenes/Synthesis%20of%20azobenzenes%20-%20the%20coloured%20pieces%20of%20molecular%20materials.pdf

Synthesis of azobenzenes: the coloured pieces of molecular materials

Traditional organic synthesis relies heavily on organic solvents for a multitude of tasks, including dissolving the components and facilitating chemical reactions, because many reagents and reactive species are incompatible or immiscible with water. Given that they are used in vast quantities as compared to reactants, solvents have been the focus of environmental concerns. Along with reducing the environmental impact of organic synthesis, the use of water as a reaction medium also benefits chemical processes by simplifying operations, allowing mild reaction conditions, and sometimes delivering unforeseen reactivities and selectivities. After the “watershed” in organic synthesis revealed the importance of water, the development of water-compatible catalysts has flourished, triggering a quantum leap in water-centered organic synthesis. Given that organic compounds are typically practically insoluble in water, simple extractive workup can readily separate a water-soluble homogeneous catalyst as an aqueous so...

Catalytic Organic Reactions in Water toward Sustainable Society

An efficient and one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by InCl3·3H2O

An efficient and one-pot synthesis of imidazolines and benzimidazoles via anaerobic oxidation of carbon–nitrogen bonds in water

By applying a combination of triflate, vinyltin, and Pd° chemistry, we have resolved this problem in the terpyridine series, and a convenient synthesis of 4'-vinylterpy from ethyl 2-pyridinecarboxylate in a reasonable overall yield is described in this paper

Synthesis of 4'-vinyl-2,2':6'2″-terpyridine

Dehydration of oximes and amides to nitriles was carried out using the AlCl3·6H2O/KI/H2O/CH3CN system. It produced isoquinoline derivatives 8a−c (Bischler Naperialski reaction) when reacted with amides 7a−c in hydrated media. Also, the keto oximes produced anilides (Beckmann rearrangement) with the system under the same reaction conditions.

AlCl3·6H2O/KI/H2O/CH3CN: A New Alternate System for Dehydration of Oximes and Amides in Hydrated Media

I2/surfactant/water system deprotecting oximes and imines to the corresponding carbonyl compounds under neutral conditions in water at 25−40 °C with very high to excellent yields.

Dilip Konwar

Papers

An efficient and one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by InCl3·3H2O

An efficient and one-pot synthesis of imidazolines and benzimidazoles via anaerobic oxidation of carbon–nitrogen bonds in water

Synthesis of 4'-vinyl-2,2':6'2″-terpyridine

AlCl3·6H2O/KI/H2O/CH3CN: A New Alternate System for Dehydration of Oximes and Amides in Hydrated Media

Surfactant/I2/water: an efficient system for deprotection of oximes and imines to carbonyls under neutral conditions in water.