Showing papers in "Tetrahedron Letters in 2008"

TL;DR: In this article, a series of hydroxyl functionalized ionic liquids (HFILs) were synthesized and characterized and showed efficient reactivity and reusability toward the coupling of epoxide and CO(2) without any additional co-catalyst and organic solvent.

TL;DR: InCl 3 ·3H 2 O was found to be a mild and effective catalyst for the efficient, one-pot, three component synthesis of 2,4,5-trisubstituted imidazoles at room temperature as discussed by the authors.

TL;DR: A new and powerful glycosylation protocol with Glycosyl ortho-alkynylbenzoates as donors and Ph3PAuOTf as a promoter is disclosed.

TL;DR: In this article, a series of 2,3-dihydroquinazolin-4(1H)-and quinazolin 4(3H)-ones were synthesized by one-pot reaction using isatoic anhydride, ammonium acetate (or amines), and aldehydes in ethanol or in DMSO under mild conditions.

TL;DR: In this paper, a carbon-carbon bond was established between a 1-alkyl-3-methyl-imidazolium ionic liquid and cellulose in alkylmethylimidazolate ILs.

TL;DR: An environmentally benign four-component reaction in aqueous medium at room temperature has been developed for the synthesis of 6-amino-5-cyano-3-methyl-4-aryl/heteroaryl-2H,4H-dihydropyrano[2,3-c]pyrazoles as discussed by the authors.

TL;DR: In this article, the synthesis of 1,2,4,5-tetrasubstituted imidazoles using benzil, an aromatic aldehyde and an amine in the presence of ammonium acetate is described.

TL;DR: NiCl2·6H2O efficiently catalyzes the C–S bond formation by the cross-coupling of aryl iodides with thiols in tetrabutylammonium bromide in excellent yield.

TL;DR: In this article, the [3+2] cycloaddition between various nitriles and trimethylsilyl azide proceeds smoothly in the presence of a Cu I catalyst in DMF/MeOH, to give the corresponding 5-substituted 1 H -tetrazoles in good to high yields.

TL;DR: An efficient one-pot condensation of β-naphthol, aldehydes, and cyclic 1,3-dicarbonyl compounds has been achieved with strontium triflate as a catalyst, thus a variety of 8,9,10,12-tetrahydrobenzo derivatives were prepared in good yields as discussed by the authors.

TL;DR: The chemosensor has shown a selective response to Hcy or Cys over other various amino acids via a ring formation of thiazinane or thiazolidine, and the fluorescent intensity was completely quenched through a photo-induced electron transfer.

TL;DR: In this paper, the use of triphenylphosphine (TPP) as a new catalyst for the one-pot Biginelli reaction coupling of β-ketoesters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones/thiones was reported.

TL;DR: In this paper, triflate-catalyzed reactions of phenylene-1,2-diamines and 1, 2-diketones produce quinoxalines in excellent to quantitative yields.

TL;DR: In this article, the direct arylation of 1,3-benzoazole compounds with aryl iodides is effectively promoted by CuI with use of PPh 3 and Na 2 CO 3 or K 3 PO 4 as ligand and base, respectively, in DMF or DMSO to produce the corresponding 2-arylated products with good yields.

TL;DR: Alkyl and aryl amines are converted smoothly to the corresponding isothiocyanates via the dithiocarbamates in good to excellent yields using di- tert -butyl dicarbonate (Boc 2 O) and 1−3 ǫ% of DMAP or DABCO as catalyst as mentioned in this paper.

TL;DR: The first synthetically useful protocol for the oxidative esterification of aldehydes with equimolar amounts of primary and secondary alcohols at room temperature catalysed by N-heterocyclic carbenes is reported in this paper.

TL;DR: N-Acetylindoles can be oxidatively coupled with arenes such as benzene or pentafluorobenzene in dioxane to produce selective arylation at indole's 2-position.

TL;DR: A polystyrene-supported NHC-Ag(I) catalyst for the three-component coupling reactions of aldehydes, alkynes, and amines was described in this paper.

TL;DR: In this article, a chiral (S )-proline modified task-specific ionic liquid has been designed and synthesized as an efficient recoverable organocatalyst for the direct asymmetric aldol reaction between cycloalkanones and aromatic aldehydes in the presence of water.

TL;DR: A series of pyrrolidine-based chiral pyridinium ionic liquids (ILs) have been developed by using commercially available (S)-(2-aminomethyl)-1-N-Boc-pyrrinium as discussed by the authors.

TL;DR: In this article, an efficient and general one-pot procedure for the synthesis of pyrazoles from acid chlorides, terminal alkynes and hydrazines via a coupling and cyclocondensation sequence was described.

TL;DR: N-Formylation of anilines has efficiently been carried out at room temperature in excellent yields by treatment with formic acid in polyethylene glycol (PEG-400) with no additional solvent and catalyst required.

TL;DR: In this paper, an efficient synthesis of polyfunctionalized 4H-pyrans is carried out in one pot through condensation of an aldehyde, malononitrile, and an active methylenic diketo compound using a heterogeneous strong basic Mg/La mixed oxide catalyst.

TL;DR: An efficient three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in nearly quantitative yields using nanocrystalline CuO as a catalyst is described in this article.

TL;DR: A cyanide selective microfluidic platform, in which fluorescent chemodosimeter 1 displayed a selective green fluorescence upon the addition of cyanide, was introduced, and the practical use of the probe was demonstrated by its application to the detection of cyanides in the living cells.

TL;DR: In this paper, an expeditious room temperature synthesis of pyrazoles and diazepines by condensation of hydrazines/hydrazides and diamines with various 1,3-diketones is described.

TL;DR: SbCl 3 adsorbed on Al 2 O 3 is found to be an efficient and recyclable catalyst in promoting three-component coupling reactions of aldehydes, amines, and dialkylphosphites to afford the corresponding α-aminophosphonates in high yields.

TL;DR: Using hydrogen peroxide as a key oxidant, catalytic oxidative amidation between aldehydes and amines was effectively carried out with PdCl 2 -xantophos as a catalyst in methanol under acidic conditions as mentioned in this paper.

TL;DR: In this paper, tricaprylmethylammonium chloride (Aliquat 336 ©) and selected Bronsted acids were synthesized by a sustainable, simple and cost-saving deprotonation-metathesis route.

TL;DR: A simple fluorescent sensor has been developed for the ratiometric recognition of Mg 2+ in semi-aqueous solution at pH 7.0 as mentioned in this paper, which can detect conditions such as hypermagnesaemia.