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Dinesh Babu Somasundaram
Researcher at University of Oklahoma Health Sciences Center
Publications - 21
Citations - 211
Dinesh Babu Somasundaram is an academic researcher from University of Oklahoma Health Sciences Center. The author has contributed to research in topics: Neuroblastoma & Cancer research. The author has an hindex of 7, co-authored 16 publications receiving 143 citations. Previous affiliations of Dinesh Babu Somasundaram include Manipal University & University of Oklahoma.
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BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.
Kumaravel Mohankumar,Subhashree Sridharan,Sankar Pajaniradje,Vivek Singh,Larance Ronsard,Akhil C. Banerjea,Dinesh Babu Somasundaram,Mohane Selvaraj Coumar,Latha Periyasamy,Rukkumani Rajagopalan,Rukkumani Rajagopalan +10 more
TL;DR: Investigation of the inhibitory effects of BDMC-A, an analog of curcumin, on invasion, angiogenesis and metastasis markers using in vitro with MCF-7 cells and in silico studies proved that BD MC-A has more potential thanCurcumin.
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Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease
Satish Kumar Ramraj,Sheeja Aravindan,Dinesh Babu Somasundaram,Terence S. Herman,Mohan Natarajan,Natarajan Aravindan +5 more
TL;DR: For the first time, serum-circulating miRNAs that predict the switch from favorable to HR-NB are identified and imply that these miRNAAs could play a functional role in tumor progression.
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Impact of di-(2-ethylhexyl) phthalate on the uterus of adult Wistar rats.
Dinesh Babu Somasundaram,Dinesh Babu Somasundaram,K Manokaran,K Manokaran,Benson Chellakkan Selvanesan,Benson Chellakkan Selvanesan,RS Bhaskaran,RS Bhaskaran +7 more
TL;DR: Adult rats were exposed to DEHP and its effects on the uterus was evaluated, and structural abnormalities exhibited the structural abnormalities such as decrease in diameter, thinning of the layers and disruption in the glandular epithelium.
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Cancer stem cells in neuroblastoma therapy resistance.
Natarajan Aravindan,Drishti Jain,Dinesh Babu Somasundaram,Terence S. Herman,Sheeja Aravindan +4 more
TL;DR: This review presents the current understanding of NB-CSCs, their intrinsic role in tumorigenesis, their function in disease progression, and their influence on acquired therapy resistance and tumor evolution, and the development of a CSC-targeted therapeutic approach.
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Lactational Exposure to Di (2-ethylhexyl) Phthalate Impairs the Ovarian and Uterine Function of Adult Offspring Rat.
Dinesh Babu Somasundaram,Benson Chellakkan Selvanesan,Ilangovan Ramachandran,Ravi Sankar Bhaskaran +3 more
TL;DR: It is suggested that lactational exposure to DEHP has transgenerational effect on female reproductive system and this finding suggest that lactating dams were exposed via oral gavage to corn oil (vehicle) and DEHP from postnatal day 1 to 21, and the effects were evaluated in the ovary and uterus of F1 progeny rats.