S
Subhashree Sridharan
Researcher at Pondicherry University
Publications - 9
Citations - 180
Subhashree Sridharan is an academic researcher from Pondicherry University. The author has contributed to research in topics: Curcumin & MCF-7. The author has an hindex of 6, co-authored 9 publications receiving 152 citations. Previous affiliations of Subhashree Sridharan include University of Texas MD Anderson Cancer Center.
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Mechanism of apoptotic induction in human breast cancer cell, MCF-7, by an analog of curcumin in comparison with curcumin – An in vitro and in silico approach
Kumaravel Mohankumar,Sankar Pajaniradje,Subhashree Sridharan,Vivek Singh,Larance Ronsard,Akhil C. Banerjea,Chellakkan Selvanesan Benson,Mohane Selvaraj Coumar,Rukkumani Rajagopalan +8 more
TL;DR: Overall results showed that BDMC-A induced apoptosis more effectively compared to curcumin and the activity can be attributed to the presence of hydroxyl group in the ortho position in its structure.
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BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.
Kumaravel Mohankumar,Subhashree Sridharan,Sankar Pajaniradje,Vivek Singh,Larance Ronsard,Akhil C. Banerjea,Dinesh Babu Somasundaram,Mohane Selvaraj Coumar,Latha Periyasamy,Rukkumani Rajagopalan,Rukkumani Rajagopalan +10 more
TL;DR: Investigation of the inhibitory effects of BDMC-A, an analog of curcumin, on invasion, angiogenesis and metastasis markers using in vitro with MCF-7 cells and in silico studies proved that BD MC-A has more potential thanCurcumin.
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Apoptosis induction by an analog of curcumin (BDMC-A) in human laryngeal carcinoma cells through intrinsic and extrinsic pathways
Kumaravel Mohankumar,Sankar Pajaniradje,Subhashree Sridharan,Vivek Singh,Larance Ronsard,Akhil C. Banerjea,Benson Chellakkan Selvanesan,Mohane Selvaraj Coumar,Latha Periyasamy,Rukkumani Rajagopalan +9 more
TL;DR: It is found that BDMC-A can induce apoptosis in Hep-2 laryngeal carcinoma cells more effectively than curcumin, and that this activity can be attributed to the presence of a hydroxyl group at the ortho position within this compound.
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Neuroprotective effect of Valeriana wallichii rhizome extract against the neurotoxin MPTP in C57BL/6 mice
Subhashree Sridharan,Kumaravel Mohankumar,Syam Praveen Kumar Jeepipalli,Divya Sankaramourthy,Larance Ronsard,Kavimani Subramanian,Manivasagam Thamilarasan,Kumar Raja,Varshney Khub Chandra,Sudha Rani Sadras +9 more
TL;DR: Conclusively, V. wallichii rhizome extract has the potential to mitigate oxidative stress and inflammatory damage in PD.
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Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction.
Larance Ronsard,Nilanjana Ganguli,Vivek Singh,Kumaravel Mohankumar,Kumaravel Mohankumar,Tripti Rai,Subhashree Sridharan,Subhashree Sridharan,Sankar Pajaniradje,Binod Kumar,Devesh Rai,Suhnrita Chaudhuri,Mohane Selvaraj Coumar,Vishnampettai G. Ramachandran,Akhil C. Banerjea +14 more
TL;DR: The co-evolution pattern of Tat and predominant nucleotides for Tat activity is highlighted, facilitating the identification of genetic determinants for the attenuation of viral gene expression.