D
Dinesh K. Dhull
Researcher at Panjab University, Chandigarh
Publications - 14
Citations - 709
Dinesh K. Dhull is an academic researcher from Panjab University, Chandigarh. The author has contributed to research in topics: Neuroprotection & Oxidative stress. The author has an hindex of 11, co-authored 14 publications receiving 521 citations. Previous affiliations of Dinesh K. Dhull include National Institute of Mental Health and Neurosciences.
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Journal ArticleDOI
Current knowledge and pharmacological profile of berberine: An update
Anil Kumar,Ekavali,Kanwaljit Chopra,Madhurima Mukherjee,Raghavender Pottabathini,Dinesh K. Dhull +5 more
TL;DR: Clinical trials with respect to neurological disorders need to be undertaken to exploit the beneficiary effects of berberine against serious disorders such as Alzheimer's and Parkinson's disease and to draw a complete safety profile of berbertine and strengthen its applicability.
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Therapeutic potential of mGluR5 targeting in Alzheimer's disease.
TL;DR: The potential of mGluR5, a metabotropic glutamatergic receptor, in understanding the mechanism underlying the neuronal death and neuroinflammation in AD is highlighted and the potential of this receptor as target for treating AD is discussed.
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Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: Possible neuroprotective mechanisms
Deepak Bhateja,Dinesh K. Dhull,Aneet Gill,Akramdeep Sidhu,Saurabh Sharma,B. Krishna Reddy,Satyanarayana S.V. Padi +6 more
TL;DR: The results showed that receptor dependent neuroprotective effects of fenofibrate in 3-NP administered rats provide a new evidence for a role of PPAR-α activation in neuroprotection that is attributed by modulating oxidative stress and inflammation.
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Neuroprotective Effect of Cyclooxygenase Inhibitors in ICV-STZ Induced Sporadic Alzheimer’s Disease in Rats
Dinesh K. Dhull,Ankur Jindal,Rakesh K. Dhull,Saurabh Aggarwal,Deepak Bhateja,Satyanarayana S.V. Padi +5 more
TL;DR: It is demonstrated for the first time that both cyclooxygenase-1 and cyclo oxygenogenase-2 isoforms, but not cyclo Oxygenase3, are involved in the progression of neuronal damage in intracerebroventricular streptozotocin-treated rats.
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Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients
Pooja-Shree Mishra,Dinesh K. Dhull,Dinesh K. Dhull,Atchayaram Nalini,K. Vijayalakshmi,Talakad N. Sathyaprabha,Phalguni Anand Alladi,Trichur R. Raju +7 more
TL;DR: It is demonstrated that the astroglial cells contribute to the neuroinflammation-mediated neurodegeneration in the in vitro model of sporadic ALS.