Human erythrocyte hemolysis induced by selenium and tellurium compounds increased by GSH or glucose: a possible involvement of reactive oxygen species.

Antinociceptive properties of acetylenic thiophene and furan derivatives: evidence for the mechanism of action.

Background
Rheumatoid arthritis (RA) is an autoimmune disease with unknown etiology. Anticitrullinated protein autoantibody has been documented as a highly specific autoantibody associated with RA. Protein arginine deiminase type 4 (PAD4) is the enzyme responsible for catalyzing the conversion of peptidylarginine into peptidylcitrulline. PAD4 is a new therapeutic target for RA treatment. In order to search for inhibitors of PAD4, structure-based virtual screening was performed using LIDAEUS (Ligand discovery at Edinburgh university). Potential inhibitors were screened experimentally by inhibition assays.

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Discovery of a new class of inhibitors for the protein arginine deiminase type 4 (PAD4) by structure-based virtual screening

Seleno- and telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16/FOXO pathway.

Synthesis and application of chiral β‐amino disulfides as ligands for the enantioselective addition of diethylzinc to aldehydes

Vinylic Tellurides: From Preparation to Their Applicability in Organic Synthesis

“One-Pot” Synthesis of Chiral N-Protected α-Amino Acid Derived 1,2,4-Oxadiazoles.

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Diogo S. Luedtke

Papers

Vinylic Tellurides: From Preparation to Their Applicability in Organic Synthesis

“One-Pot” Synthesis of Chiral N-Protected α-Amino Acid Derived 1,2,4-Oxadiazoles.

Synthesis of New Chiral Aliphatic Amino Diselenides and Their Application as Catalysts for the Enantioselective Addition of Diethylzinc to Aldehydes.

New Acetylenic Furan Derivatives: Synthesis and Antiinflammatory Activity.

Nucleophilic Addition of Potassium Alkynyltrifluoroborates to D‐Glucal Mediated by BF3·OEt2: Highly Stereoselective Synthesis of α‐C‐Glycosides.