C
Cristina W. Nogueira
Researcher at Universidade Federal de Santa Maria
Publications - 520
Citations - 18366
Cristina W. Nogueira is an academic researcher from Universidade Federal de Santa Maria. The author has contributed to research in topics: Diphenyl diselenide & Ascorbic acid. The author has an hindex of 59, co-authored 503 publications receiving 16655 citations. Previous affiliations of Cristina W. Nogueira include Institute of Molecular Pathology and Immunology of the University of Porto & Harvard University.
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Journal ArticleDOI
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
TL;DR: The development of new organochalcogens with higher thiol-peroxidase activity that can use other non-toxic thiol reducing agents, such as N-acetylcysteine instead of glutathione, will permit the investigation of the co-administration of organochAlcogens and thiols as a formulation for antioxidant therapy.
Journal ArticleDOI
Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice
Maria Caroline Jacques‐Silva,Cristina W. Nogueira,Luis Carlos Broch,Erico M.M. Flores,João Rocha +4 more
TL;DR: It is shown that ascorbic acid can reverse some alterations caused by in vivo selenium exposure, but not ALA-D inhibition, and this study suggests that vitamin C may have a protective role in organodiselenide intoxication.
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Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds
Cristina W. Nogueira,João Rocha +1 more
TL;DR: The potential therapeutic use of simple organoselenium compounds has not yet been sufficiently explored and this class of compounds cannot discard as promising pharmaceutical agents, in effect, the future of the organochalcogens as pharmacological agents will depend on more detailed toxicological studies in the oncoming years.
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Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene.
Minjung Kim,Joseph D. Gans,Cristina W. Nogueira,Cristina W. Nogueira,Audrey Wang,Jihye Paik,Bin Feng,Cameron Brennan,William C. Hahn,William C. Hahn,Carlos Cordon-Cardo,Stephan N. Wagner,Thomas J. Flotte,Lyn M. Duncan,Scott R. Granter,Lynda Chin +15 more
TL;DR: In this article, Nedd9, an adaptor protein related to p130CAS, was identified as the only gene within the minimal common region that exhibited amplification-associated overexpression.
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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
Richard S. Maser,Bhudipa Choudhury,Peter J. Campbell,Bin Feng,Kwok-Kin Wong,Alexei Protopopov,Jennifer O'Neil,Alejandro Gutierrez,Elena Ivanova,Ilana Perna,Eric Lin,Vidya Mani,Shan Jiang,Kate McNamara,Sara Zaghlul,Sarah Edkins,Claire Stevens,Cameron Brennan,Eric S. Martin,Ruprecht Wiedemeyer,Omar Kabbarah,Cristina W. Nogueira,Gavin Histen,Jon C. Aster,Marc R. Mansour,Veronique Duke,Letizia Foroni,Adele K. Fielding,Anthony H. Goldstone,Jacob M. Rowe,Yaoqi A. Wang,A. Thomas Look,Michael R. Stratton,Lynda Chin,P. Andrew Futreal,Ronald A. DePinho +35 more
TL;DR: The results indicate that murine and human tumours experience common biological processes driven by orthologous genetic events in their malignant evolution.