D
Dipanwita Mitra
Researcher at University of Mississippi Medical Center
Publications - 19
Citations - 546
Dipanwita Mitra is an academic researcher from University of Mississippi Medical Center. The author has contributed to research in topics: Heparan sulfate & Viral entry. The author has an hindex of 7, co-authored 15 publications receiving 205 citations.
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Journal ArticleDOI
Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives.
Ritesh Tandon,Joshua S. Sharp,Fuming Zhang,Vitor H. Pomin,Nicole M. Ashpole,Dipanwita Mitra,Martin G. McCandless,Weihua Jin,Hao Liu,Poonam Sharma,Robert J. Linhardt +10 more
TL;DR: Several sulfated polysaccharides show potent anti-SARS-CoV-2 activity and can be developed for prophylactic as well as therapeutic purposes, according to structure-based differences in antiviral activity and affinity to SGP.
Posted ContentDOI
Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
Ritesh Tandon,Joshua S. Sharp,Fuming Zhang,Vitor H. Pomin,Nicole M. Ashpole,Dipanwita Mitra,Weihua Jin,Hao Liu,Poonam Sharma,Robert J. Linhardt +9 more
TL;DR: The low serum bioavailability of intranasally administered UFH, along with data suggesting that the nasal epithelium is a portal for initial infection and transmission, suggest that intranASal administration of UFH may be an effective and safe prophylactic treatment.
Journal ArticleDOI
The rapid diagnosis and effective inhibition of coronavirus using spike antibody attached gold nanoparticles
Avijit Pramanik,Ye Gao,Shamily Patibandla,Dipanwita Mitra,Martin G. McCandless,Lauren A. Fassero,Kalein Gates,Ritesh Tandon,Paresh Chandra Ray +8 more
TL;DR: The reported data show that antibody attached gold nanoparticles bind to SARS-CoV-2 spike protein, thereby inhibiting the virus from binding to cell receptors, which stops virus infection and spread and has the capability to destroy the lipid membrane of the virus.
Journal ArticleDOI
Aptamer Conjugated Gold Nanostar-Based Distance-Dependent Nanoparticle Surface Energy Transfer Spectroscopy for Ultrasensitive Detection and Inactivation of Corona Virus.
Avijit Pramanik,Ye Gao,Shamily Patibandla,Dipanwita Mitra,Martin G. McCandless,Lauren A. Fassero,Kalein Gates,Ritesh Tandon,Paresh Chandra Ray +8 more
TL;DR: In this article, the authors demonstrate that Rhodamine 6G (Rh-6G) dye conjugated DNA aptamer-attached gold nanostar (GNS)-based distance-dependent nanoparticle surface energy transfer (NSET) spectroscopy has the capability of rapid diagnosis of specific SARS-CoV-2 spike recombinant antigen or SARS -CoV -2 spike protein pseudotyped baculovirus within 10 min.
Journal ArticleDOI
The structure-activity relationship of the interactions of SARS-CoV-2 spike glycoproteins with glucuronomannan and sulfated galactofucan from Saccharina japonica.
Weihua Jin,Weihua Jin,Wenjing Zhang,Dipanwita Mitra,Martin G. McCandless,Poonam Sharma,Ritesh Tandon,Fuming Zhang,Robert J. Linhardt +8 more
TL;DR: The sulfated galactofucan and glucuronomannan showed strong binding ability to SARS-CoV-2 SGPs, suggesting that these polysaccharides might be good candidates for preventing and/or treating SARS.