D
Dominic Cavlan
Researcher at Queen Mary University of London
Publications - 4
Citations - 118
Dominic Cavlan is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Adrenal cortex & Cancer. The author has an hindex of 3, co-authored 4 publications receiving 98 citations.
Papers
More filters
Book ChapterDOI
Adrenocortical development, maintenance, and disease.
Rebecca Yates,Harshini Katugampola,Dominic Cavlan,Katy Cogger,Eirini Meimaridou,Claire Hughes,Louise A. Metherell,Leonardo Guasti,Peter J. King +8 more
TL;DR: The transcriptional networks and signaling pathways involved in development and maintenance of the gland and in its pathology are discussed in the light of the wealth of physiological information gathered in studies of human and rodent adrenal development and function.
Journal ArticleDOI
Dlk1 Up-Regulates Gli1 Expression in Male Rat Adrenal Capsule Cells Through the Activation of β1 Integrin and ERK1/2
Leonardo Guasti,Dominic Cavlan,Kathryn F. Cogger,Zahida Banu,Amreen Shakur,Salima Latif,Peter J. King +6 more
TL;DR: It is demonstrated that Shh and Dlk1 are coexpressed in the outer undifferentiated zone of the male rat adrenal and that DlK1 signals to the adrenal capsule, activating glioma-associated oncogene homolog 1 transcription in a β1 integrin- and Erk1/2-dependent fashion.
Journal ArticleDOI
Androgen- and Estrogen-Secreting Adrenal Cancers
TL;DR: When an adrenal tumor is found to secrete androgens or estrogens to excess, it can be difficult to confirm that it is a cancer, as there is significant overlap in the secretory patterns and imaging appearances of benign and malignant disease.