D
Dominique Bourgeois
Researcher at University of Grenoble
Publications - 119
Citations - 6042
Dominique Bourgeois is an academic researcher from University of Grenoble. The author has contributed to research in topics: Chromophore & Fluorescence. The author has an hindex of 41, co-authored 110 publications receiving 5559 citations. Previous affiliations of Dominique Bourgeois include European Synchrotron Radiation Facility & Centre national de la recherche scientifique.
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Journal ArticleDOI
Photolysis of the carbon monoxide complex of myoglobin: nanosecond time-resolved crystallography.
Vukica Šrajer,Tsu Yi Teng,T. Ursby,Claude Pradervand,Zhong Ren,Shin-ichi Adachi,Wilfried Schildkamp,Dominique Bourgeois,Michael Wulff,Keith Moffat +9 more
TL;DR: Time-resolving experiments reveal the structures of myoglobin photoproducts, provide a structural foundation to spectroscopic results and molecular dynamics calculations, and demonstrate that time-resolved macromolecular crystallography can elucidate the structural bases of biochemical mechanisms on the nanosecond time scale.
Journal ArticleDOI
Protein Conformational Relaxation and Ligand Migration in Myoglobin: A Nanosecond to Millisecond Molecular Movie from Time-Resolved Laue X-ray Diffraction†
Srajer,Z. Ren,T.-Y. Teng,Marius Schmidt,T. Ursby,Dominique Bourgeois,Claude Pradervand,Schildkamp W,Michael Wulff,Keith Moffat +9 more
TL;DR: These results demonstrate that structural changes as small as 0.2 A and populations of CO docking sites of 10% can be detected by time-resolved X-ray diffraction.
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Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle.
Benjamin Perman,Vukica Šrajer,Zhong Ren,Tsu-yi Teng,Claude Pradervand,Thomas Ursby,Dominique Bourgeois,F. Schotte,Michael Wulff,Remco Kort,Klaas J. Hellingwerf,Keith Moffat +11 more
TL;DR: Direct structural evidence is provided for the initial processes of transduction of light energy, which ultimately translate into a physiological signal.
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Structural characterization of IrisFP, an optical highlighter undergoing multiple photo-induced transformations
Virgile Adam,Mickaël Lelimousin,Susan Boehme,Guillaume Desfonds,Karin Nienhaus,Martin J. Field,Joerg Wiedenmann,Sean McSweeney,G. Ulrich Nienhaus,Dominique Bourgeois +9 more
TL;DR: In this article, the Phe-173-Ser mutant of the tetrameric variant of EosFP, named IrisFP, was characterized using both crystallography and (in crystallo) spectroscopy.
Journal ArticleDOI
Complex landscape of protein structural dynamics unveiled by nanosecond Laue crystallography.
Dominique Bourgeois,Beatrice Vallone,F. Schotte,Alessandro Arcovito,Adriana E. Miele,Giuliano Sciara,Micheal Wulff,Philip A. Anfinrud,Maurizio Brunori +8 more
TL;DR: It is proposed that the extended relaxation of the globin moiety reflects reequilibration among conformational substates known to play an essential role in controlling protein function.