S
Stanley J. Szefler
Researcher at University of Colorado Denver
Publications - 578
Citations - 40675
Stanley J. Szefler is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Asthma & Exhaled nitric oxide. The author has an hindex of 99, co-authored 554 publications receiving 37481 citations. Previous affiliations of Stanley J. Szefler include Anschutz Medical Campus & University of California, San Francisco.
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Journal ArticleDOI
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.
Helen K. Reddel,D. Robin Taylor,Eric D. Bateman,Louis-Philippe Boulet,Homer A. Boushey,William W. Busse,Thomas B. Casale,Pascal Chanez,Paul L. Enright,Peter G. Gibson,Johan C. de Jongste,Huib A. M. Kerstjens,Stephen C. Lazarus,Mark L Levy,Paul M. O'Byrne,Martyn R Partridge,Ian D. Pavord,Malcolm R. Sears,Peter J. Sterk,Stuart W. Stoloff,Sean D. Sullivan,Stanley J. Szefler,Mike Thomas,Sally E. Wenzel +23 more
TL;DR: New definitions for asthma control, severity, and exacerbations are developed, based on current treatment principles and clinical and research relevance, to provide a basis for a multicomponent assessment of asthma by clinicians, researchers, and other relevant groups in the design, conduct, and evaluation of clinical trials, and in clinical practice.
Journal ArticleDOI
Long-term effects of budesonide or nedocromil in children with asthma.
Stanley J. Szefler,Scott T. Weiss,James Tonascia,N. Franklin Adkinson,Bruce G. Bender,Reuben M. Cherniack,Michele Donithan,H William Kelly,J. Reisman,Gail G. Shapiro,Alice L. Sternberg,R.C. Strunk,Virginia S. Taggart,Mark L. Van Natta,Robert A. Wise,Margaret Wu,Robert S. Zeiger +16 more
TL;DR: In children with mild-to-moderate asthma, neither budesonide nor nedocromil is better than placebo in terms of lung function, but inhaled budesonides improves airway responsiveness and provides better control of asthma than placebo or nedOCromil.
Journal ArticleDOI
Long-term inhaled corticosteroids in preschool children at high risk for asthma.
Theresa W. Guilbert,Wayne J. Morgan,Robert S. Zeiger,Robert S. Zeiger,David T. Mauger,Susan J. Boehmer,Stanley J. Szefler,Leonard B. Bacharier,R.F. Lemanske,Robert C. Strunk,David B. Allen,Gordon R. Bloomberg,Gregory P. Heldt,Marzena E. Krawiec,Gary L. Larsen,A.H. Liu,Vernon M. Chinchilli,Christine A. Sorkness,Lynn M. Taussig,Fernando D. Martinez +19 more
TL;DR: In preschool children at high risk for asthma, two years of inhaled-corticosteroid therapy did not change the development of asthma symptoms or lung function during a third, treatment-free year, and these findings do not provide support for a subsequent disease-modifying effect of inhaling corticosteroids after the treatment is discontinued.
Journal ArticleDOI
Proceedings of the ATS Workshop on Refractory Asthma Current Understanding, Recommendations, and Unanswered Questions
Sally E. Wenzel,John V. Fahy,Charles G. Irvin,Stephen P. Peters,Sheldon L. Spector,Stanley J. Szefler,Thomas B. Casale,Michelle M. Cloutier,Jack A. Elias,Mark C. Liu,Virginia Taggert +10 more
TL;DR: The proceedings of an American Thoracic Society (ATS)-sponsored workshop are hoped to serve as an aid to begin to define, understand, and manage these refractory patients.
Journal ArticleDOI
Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids.
Sally E. Wenzel,Stanley J. Szefler,Donald Y.M. Leung,Steven I. Sloan,Michael D. Rex,Richard J. Martin +5 more
TL;DR: Investigating the presence and type of airway inflammation in patients with severe asthma suggests that inflammation remains in severe symptomatic asthmatics despite treatment with high dose glucocorticoids, which may be due to the severity of disease, glucOCorticoid treatment, or other as yet undefined factors.