D
Donatella Santini
Researcher at University of Bologna
Publications - 330
Citations - 11968
Donatella Santini is an academic researcher from University of Bologna. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 51, co-authored 316 publications receiving 10669 citations.
Papers
More filters
Journal ArticleDOI
Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma.
Milena Urbini,Margherita Nannini,Annalisa Astolfi,Valentina Indio,Valentina Vicennati,Matilde De Luca,Giuseppe Tarantino,Federica Corso,Maristella Saponara,Lidia Gatto,Donatella Santini,Guido Di Dalmazi,Uberto Pagotto,Renato Pasquali,Andrea Pession,Guido Biasco,Maria Abbondanza Pantaleo +16 more
TL;DR: Additional somatic passenger mutations can be associated with known susceptibility VHL, NF1, and RET genes in PCCs, and a wide number of germline variants with still unknown clinical significance can be detected in these patients.
Journal ArticleDOI
The p53-mediated sensitivity of cancer cells to chemotherapeutic agents is conditioned by the status of the retinoblastoma protein.
Massimo Derenzini,Elisa Brighenti,Giulio Donati,Manuela Vici,Claudio Ceccarelli,Donatella Santini,Mario Taffurelli,Lorenzo Montanaro,Davide Treré +8 more
TL;DR: It is demonstrated that the p53‐mediated response to chemotherapeutic agents induces a cytostatic/cytotoxic effect only in cancers with unaltered pRb pathway, and the p 53 status can actually predict the clinical outcome in this group of cancer patients.
Journal ArticleDOI
Comparison of HPV sign Genotyping Test with INNO-LiPA HPV Genotyping Extra assay on histologic and cytologic cervical specimens☆
Daniela Barbieri,M. Nocera,Giorgio Gallinella,Giovanna Angela Gentilomi,M. Plazzi,Sivano Costa,Donatella Santini,Simona Venturoli +7 more
TL;DR: HPV sign is a promising method for HPV genotyping and has revealed advantages in detecting a broad spectrum of HPV types and variants.
Journal ArticleDOI
Cell Proliferation in Breast Cancer is a Major Determinant of Clinical Outcome in Node-positive but Not in Node-negative Patients
Davide Treré,Claudio Ceccarelli,Mario Migaldi,Donatella Santini,Mario Taffurelli,Elena Tosti,Pasquale Chieco,Massimo Derenzini +7 more
TL;DR: Results show that in breast carcinoma the cell growth fraction and the cell proliferation rate have a different prognostic impact with respect to the lymph node status and are major determinants of clinical outcome in node-positive patients only.
Journal ArticleDOI
Leiomyomatosis in pelvic lymph nodes
TL;DR: A case of leiomyomatosis in obturator lymph nodes, without uterine leIomyomas or disseminated peritoneal leiomers, that occurred in a woman with an endometrial adenocarcinoma and an ovarian endometrioid carcinoma is reported.