D
Donatella Santini
Researcher at University of Bologna
Publications - 330
Citations - 11968
Donatella Santini is an academic researcher from University of Bologna. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 51, co-authored 316 publications receiving 10669 citations.
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Journal ArticleDOI
Placing mitochondrial DNA mutations within the progression model of type I endometrial carcinoma
Flora Guerra,Ivana Kurelac,Antonella Cormio,Roberta Zuntini,Laura Benedetta Amato,Claudio Ceccarelli,Donatella Santini,Gennaro Cormio,Flavio Fracasso,Luigi Selvaggi,Leonardo Resta,Marcella Attimonelli,Maria Nicola Gadaleta,Giuseppe Gasparre +13 more
TL;DR: Protein expression analysis revealed an increase in mitochondrial biogenesis and activation of oxidative stress response mechanisms in tumor tissues, but not in hyperplasia, in correlation with the occurrence of pathogenic mtDNA mutations.
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Total pancreatectomy: indications, operative technique, and results: a single centre experience and review of literature.
Riccardo Casadei,Francesco Monari,Salvatore Buscemi,Marco Laterza,Claudio Ricci,Daniela Rega,Marielda D'Ambra,Raffaele Pezzilli,Lucia Calculli,Donatella Santini,Francesco Minni +10 more
TL;DR: Its indications are increasing because of the more frequent diagnose of pancreatic disease that involved the whole gland as well as intraductal pancreatic mucinous neoplasm, neuroendocrine tumors and pancreatic metastases from renal cell cancer.
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The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach
Marco Trinchera,Nadia Malagolini,Mariella Chiricolo,Donatella Santini,Francesco Minni,Anna Caretti,Fabio Dall'Olio +6 more
TL;DR: Data indicate that in colon cancer tissues Fuc-TVI is a key regulator of sLex biosynthesis which can be the target of RNA-interference-based gene knock-down approaches.
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Idiopathic myenteric ganglionitis underlying intractable vomiting in a young adult.
R. De Giorgio,Giovanni Barbara,Vincenzo Stanghellini,Rosanna Cogliandro,A Arrigoni,Donatella Santini,Claudio Ceccarelli,Beatrice Salvioli,F P Rossini,Roberto Corinaldesi +9 more
TL;DR: The case of a patient who presented with chronic intractable vomiting and weight loss associated with idiopathic myenteric ganglionitis mainly involving the stomach, and after one year of follow-up his general condition remains satisfactory.
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PPARγ and RXR ligands disrupt the inflammatory cross-talk in the hypoxic breast cancer stem cells niche.
Alessio Papi,Sabrina De Carolis,Sara Bertoni,Gianluca Storci,Virginia Sceberras,Donatella Santini,Claudio Ceccarelli,Mario Taffurelli,Marina Orlandi,Massimiliano Bonafè,Massimiliano Bonafè +10 more
TL;DR: NRs agonists disrupt the inflammatory cross‐talk of the hypoxic breast CSCs niche by abolishing the capability of hypoxic MCF7 derived exosomes to induce a pro‐inflammatory phenotype in mammary glands fibroblasts.