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Donatella Santini

Researcher at University of Bologna

Publications -  330
Citations -  11968

Donatella Santini is an academic researcher from University of Bologna. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 51, co-authored 316 publications receiving 10669 citations.

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Accurate neurosonographic prediction of brain injury in the surviving fetus after the death of a monochorionic cotwin

TL;DR: To assess the feasibility of the prenatal diagnosis using fetal neurosonography of brain injuries in the surviving fetus after the demise of a monochorionic cotwin, a large number of studies have found that this diagnosis is feasible.
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Loss of retinoblastoma tumor suppressor protein makes human breast cancer cells more sensitive to antimetabolite exposure.

TL;DR: The absence of pRB expression renders human breast cancer cells more sensitive to 5-FU and methotrexate and predicts a good clinical outcome for patients treated with adjuvant chemotherapy, and it is suggested that patients with RB-negative breast cancers should be treated with systemic chemotherapy.
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Presence and type of oncogenic human papillomavirus in classic and in differentiated vulvar intraepithelial neoplasia and keratinizing vulvar squamous cell carcinoma.

TL;DR: The absolute absence of HPV DNA in differentiated vulvar intraepithelial neoplasias and in keratinizing vulvar squamous cell carcinoma suggests a strong HPV‐independent pathway of malignant progression to invasive carcinoma.
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Quantitative p21WAF-1/p53 immunohistochemical analysis defines groups of primary invasive breast carcinomas with different prognostic indicators

TL;DR: In the P53H group, both p53 and Ki‐67 were inversely associated with both estrogen receptor (ER) and progesterone receptor (PGR), suggesting that extensive p53 immunostaining is related to poor differentiation and high proliferation.