Donna H. Korzick

TL;DR: The difference in VE/VO2 suggests a lower ventilatory threshold for the obese women, and cardiorespiratory responses of moderately obese women are increased at absolute workloads when compared to that of leaner women, HR is similar at comparable intensities of exercise.

TL;DR: Information gathered over the last 25 to 30 years has been reviewed in an attempt to identify cellular myocardial adaptations that are responsible for the observed effects of chronic dynamic exercise on the function and morphology of the heart in both normal and selected pathophysiologic settings.

TL;DR: The concept that exercise hyperemia is a local phenomenon is emphasized and that, during maximal exercise when most signals for vasoconstriction are still present, three primary control mechanisms are thought to regulate vasodilation and subsequent increases in vascular conductance: myogenic vascular control, metabolic vascular Control, and endothelium-mediated vascular control.

TL;DR: The data suggest, for the first time, that selective ERalpha activation reduces ischemic injury in the aged, estrogen-deficient heart through a mechanism involving nongenomic redistribution of ERalpha and PKCepsilon activation.

TL;DR: The results indicate, for the first time, that selective translocation of PKCalpha and PKCepsilon in response to alpha1-AR stimulation is disrupted in the senescent myocardium, and alterations in PKC-anchoring proteins may contribute to impaired PKC translocation and defective alpha 1-AR contraction in the aged rat heart.