D
Dorothy Dembiec
Researcher at University of York
Publications - 5
Citations - 1417
Dorothy Dembiec is an academic researcher from University of York. The author has contributed to research in topics: Catecholamine uptake & Nialamide. The author has an hindex of 5, co-authored 5 publications receiving 1336 citations. Previous affiliations of Dorothy Dembiec include Columbia University.
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Measurement of catalase activity in tissue extracts.
Journal Article
Tetrahydroisoquinoline alkaloids: uptake by rat brain homogenates and inhibition of catecholamine uptake
TL;DR: Observations are consistent with the point of view that tetrahydroisoquinoline alkaloids may play an important role in alcoholism.
Journal Article
Destruction of sympathetic nerve terminals by 6-hydroxydopamine: protection by 1-phenyl-3-(2-thiazolyl)-2-thiourea, diethyldithiocarbamate, methimazole, cysteamine, ethanol and n-butanol.
Gerald Cohen,Richard E. Heikkila,B Allis,F Cabbat,Dorothy Dembiec,D MacNamee,Catherine Mytilineou,B Winston +7 more
TL;DR: Protection against neurodegenerative actions of 6-hydroxydopamine or 6-aminodopamine in fully protected mice and the appearance of the nerve plexus in partially protected mice was essentially normal at 24 hours, except for infrequent large swellings.
Journal Article
The effect of pargyline and other monoamine oxidase inhibitors on blood acetaldehyde levels in ethanol-intoxicated mice.
TL;DR: Blood acetaldehyde levels in mice treated with pargyline and ethanol were strongly depressed by pyrazole, an inhibitor of alcohol dehydrogenase, and moderately to strongly depressed (49-71%) by pretreatment with phenobarbital, an inducer of liver aldehyde dehydrogenases.
Journal Article
Uptake and accumulation of 3H-6,7-dihydroxytetrahydroisoquinoline by peripheral sympathetic nerves in vivo.
TL;DR: Neuronal 3H-alkaloid was relatively protected from metabolic transformation and the relationship of these observations to a hypothesis about tetrahydroisoquinoline biosynthesis from endogenous catecholamines during ethanol metabolism is discussed.