Dörte Rother

TL;DR: It is shown that visible-light-driven, catalytic water oxidation can be used for in situ generation of H2O2 from water, rendering the peroxygenase catalytically active, allowing efficient oxyfunctionalization without stoichiometric reductants.

TL;DR: Benefits and recent advances in whole cell biocatalysis are reviewed and comment on the close proximity of reactants and catalysts as well as the inherent presence of expensive cofactors.

TL;DR: This review covers recent studies and the mechanistic understanding of stereoselective C–C bond forming thiamine diphosphate‐dependent enzymes, which has been guided by structure–function analyses based on mutagenesis studies and from influences of different substrates and organic co‐solvents on stereoselectedivity.

TL;DR: Chemoenzymatic and enzymatic cascade reactions enable the synthesis of complex stereocomplementary 1,3,4‐trisubstituted tetrahydroisoquinolines (THIQs) with three chiral centers in a step‐efficient and selective manner without intermediate purification.